Colletofragarone A2 Inhibits Cancer Cell Growth In Vivo and Leads to the Degradation and Aggregation of Mutant p53.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.2c00202
Abstract: Mutant p53 not only loses its original tumor suppressor function but also acquires new abilities regarding oncogenic progression. Therefore, the strategy of targeting mutant p53 has attracted attention for cancer therapy. We isolated colletofragarone A2… read more here.
Keywords: colletofragarone; mutant p53; cell growth; growth vivo ... See more keywords
miR-221 to modulate tumor growth in vivo and as a regulator of TGF.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.e23008
Abstract: e23008Background: Despite the advances in cancer therapy, when Prostate Cancer (PCa) progress to castration resistant phase, patients develop incurable bone metastases. Understanding the processes ... read more here.
Keywords: modulate tumor; mir 221; 221 modulate; vivo regulator ... See more keywords
Mycobacterium leprae Transcriptome During In Vivo Growth and Ex Vivo Stationary Phases
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2021.817221
Abstract: Mycobacterium leprae, the causative agent of leprosy, is an obligate intracellular pathogen primarily residing within host macrophages and Schwann cells. Whole genome sequencing predicts a highly degraded genome with approximately one third of the coding… read more here.
Keywords: growth vivo; compared mfp5; growth; mycobacterium leprae ... See more keywords