A trio has turned into a quartet: DJ-1 interacts with the IP3R-Grp75-VDAC complex to control ER-mitochondria interaction.
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DOI: 10.1016/j.ceca.2020.102186
Abstract: The outer mitochondrial membrane protein VDAC interacts with the ER protein IP3R via chaperone Grp75 to form a molecular complex that couples mitochondria to the ER and contributes to functional mitochondria-ER contacts (MERCs), essential for… read more here.
Keywords: trio turned; vdac; vdac complex; ip3r grp75 ... See more keywords