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Aspalathus linearis suppresses cell survival and proliferation of enzalutamide-resistant prostate cancer cells via inhibition of c-Myc and stability of androgen receptor

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Published in 2022 at "PLoS ONE"

DOI: 10.1371/journal.pone.0270803

Abstract: Enzalutamide, a nonsteroidal antiandrogen, significantly prolonged the survival of patients with metastatic castration-resistant prostate cancer (CRPC). However, patients receiving enzalutamide frequently develop drug resistance. Rooibos (Aspalathus linearis) is a shrub-like leguminous fynbos plant endemic to… read more here.

Keywords: proliferation; prostate; enzalutamide resistant; pca ... See more keywords