Dipeptide Mimetic of the Brain-derived Neurotrophic Factor Prevents Impairments of Neurogenesis in Stressed Mice
Sign Up to like & getrecommendations! Published in 2017 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-017-3638-9
Abstract: Brain-derived neurotrophic factor (BDNF) plays the central role in the mechanisms of regulation of neurogenesis and neuroplasticity. Impairment of these mechanisms is considered as one of the main etiological factors of depression. Dimeric dipeptide mimetic… read more here.
Keywords: brain derived; derived neurotrophic; gsb 106; stressed mice ... See more keywords
Antidepressant-like Effects of BDNF and NGF Individual Loop Dipeptide Mimetics Depend on the Signal Transmission Patterns Associated with Trk
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15030284
Abstract: Neurotrophins are considered as an attractive target for the development of antidepressants with a novel mechanism of action. Previously, the dimeric dipeptide mimetics of individual loops of nerve growth factor, NGF (GK-6, loop 1; GK-2,… read more here.
Keywords: gsb 106; dipeptide mimetics; loop; antidepressant like ... See more keywords