GSDMD (Gasdermin D) Mediates Pathological Cardiac Hypertrophy and Generates a Feed-Forward Amplification Cascade via Mitochondria-STING (Stimulator of Interferon Genes) Axis
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DOI: 10.1161/hypertensionaha.122.20004
Abstract: Background: Cardiac hypertrophy is initially an adaptive response of cardiomyocytes to neurohumoral or hemodynamic stimuli. Evidence indicates that Ang II (angiotensin II) or pressure overload causes GSDMD (gasdermin D) activation in cardiomyocytes and myocardial tissues.… read more here.
Keywords: hypertrophy; gsdmd gasdermin; cardiac hypertrophy; stimulator interferon ... See more keywords