GSDME-mediated pyroptosis promotes inflammation and fibrosis in obstructive nephropathy.
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DOI: 10.1038/s41418-021-00755-6
Abstract: Renal tubular cell (RTC) death and inflammation contribute to the progression of obstructive nephropathy, but its underlying mechanisms have not been fully elucidated. Here, we showed that Gasdermin E (GSDME) expression level and GSDME-N domain… read more here.
Keywords: inflammation fibrosis; gsdme mediated; obstructive nephropathy; gsdme ... See more keywords