Articles with "gsea" as a keyword



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GSEApy: a comprehensive package for performing gene set enrichment analysis in Python

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Published in 2022 at "Bioinformatics"

DOI: 10.1093/bioinformatics/btac757

Abstract: Abstract Motivation Gene set enrichment analysis (GSEA) is a commonly used algorithm for characterizing gene expression changes. However, the currently available tools used to perform GSEA have a limited ability to analyze large datasets, which… read more here.

Keywords: enrichment analysis; gsea; analysis; gseapy ... See more keywords
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TargeTron Inactivation of Chlamydia trachomatis gseA Results in a Lipopolysaccharide 3-Deoxy-d-Manno-Oct-2-Ulosonic Acid-Deficient Strain That Is Cytotoxic for Cells

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Published in 2023 at "Infection and Immunity"

DOI: 10.1128/iai.00096-23

Abstract: All members of the family Chlamydiaceae have lipopolysaccharides (LPS) that possess a shared carbohydrate trisaccharide antigen, 3-deoxy-d-manno-oct-2-ulosonic acid (Kdo) that is functionally uncharacterized. A single gene, genus-specific epitope (gseA), is responsible for attaching the tri-Kdo… read more here.

Keywords: kdo; microscopy; gsea; acid ... See more keywords
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Abstract 6568: Extended support for model organisms: The next frontier for the molecular signatures database

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-6568

Abstract: In 2005, we introduced the Gene Set Enrichment Analysis (GSEA) method to enable the identification and estimation of significance of activated biological pathways and processes in molecular data. Serving a community of over 300,000 registered… read more here.

Keywords: gsea; analysis; msigdb; support ... See more keywords

GSEA–SDBE: A gene selection method for breast cancer classification based on GSEA and analyzing differences in performance metrics

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Published in 2022 at "PLoS ONE"

DOI: 10.1371/journal.pone.0263171

Abstract: Motivation Selecting the most relevant genes for sample classification is a common process in gene expression studies. Moreover, determining the smallest set of relevant genes that can achieve the required classification performance is particularly important… read more here.

Keywords: classification; gsea; breast cancer; relevant genes ... See more keywords
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Factors associated with gastrointestinal side effects after liraglutide treatment for type 2 diabetes

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Published in 2023 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2023.1098032

Abstract: Aim To identify risk factors predictive of or associated with gastrointestinal side effects (GISE) of liraglutide in patients with type 2 diabetes (T2DM). Methods T2DM patients treated with liraglutide for the first time were obtained… read more here.

Keywords: associated gastrointestinal; side effects; gsea; type diabetes ... See more keywords