Articles with "gsh conjugate" as a keyword



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In Vitro and In Vivo Metabolic Activation of Tolterodine Mediated by CYP3A.

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Published in 2023 at "Chemical research in toxicology"

DOI: 10.1021/acs.chemrestox.2c00389

Abstract: Tolterodine (TOL) is an antimuscarinic drug used for the treatment of patients with overactive bladder presenting urinary frequency, urgency, and urge incontinence. During the clinical use of TOL, adverse events such as liver injury took… read more here.

Keywords: tolterodine; metabolic activation; gsh conjugate; tol ... See more keywords