Amorphous Ultra‐Small Fe‐Based Nanocluster Engineered and ICG Loaded Organo‐Mesoporous Silica for GSH Depletion and Photothermal‐Chemodynamic Synergistic Therapy
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DOI: 10.1002/adhm.202201986
Abstract: Intracellular oxidative amplification can effectively destroy tumor cells. Additionally, Fe‐mediated Fenton reaction often converts cytoplasm H2O2 to generate extensive hypertoxic hydroxyl radical (•OH), leading to irreversible mitochondrion damage for tumor celleradication, which is widely famous… read more here.
Keywords: gsh; organo mesoporous; loaded organo; icg loaded ... See more keywords
Copperphosphotungstate Doped Polyanilines Nanorods for GSH-Depletion Enhanced Chemodynamic/NIR-II Photothermal Synergistic Therapy
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DOI: 10.2147/ijn.s399026
Abstract: Introduction The high concentration of glutathione (GSH) and hydrogen peroxide (H2O2) levels within the tumor microenvironment (TME) are the major obstacle to induce the unsatisfactory anticancer treatment efficiency. The synergistic cancer therapy strategies of the… read more here.
Keywords: depletion enhanced; gsh depletion; nir photothermal; therapy ... See more keywords
Biomimetic CuS nanoparticles for radiosensitization with mild photothermal therapy and GSH-depletion
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DOI: 10.3389/fonc.2022.1054608
Abstract: Due to its non-invasive and highly effective characteristics, radiotherapy has attracted significant interest in cancer treatment. However, radioresistance of solid tumors caused by a unique tumor microenvironment diminishes the therapeutic effect of cancer radiotherapy. To… read more here.
Keywords: tumor; gsh depletion; photothermal therapy;
Synergistic Activity of Ketoconazole and Miconazole with Prochloraz in Inducing Oxidative Stress, GSH Depletion, Mitochondrial Dysfunction, and Apoptosis in Mouse Sertoli TM4 Cells
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DOI: 10.3390/ijms23105429
Abstract: Triazole and imidazole fungicides represent an emerging class of pollutants with endocrine-disrupting properties. Concerning mammalian reproduction, a possible causative role of antifungal compounds in inducing toxicity has been reported, although currently, there is little evidence… read more here.
Keywords: apoptosis; oxidative stress; mitochondrial dysfunction; dysfunction ... See more keywords