GSH/GSSG redox couple plays central role in aryl hydrocarbon receptor‐dependent modulation of cytochrome P450 1A1
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22164
Abstract: The redox regulation of aryl hydrocarbon receptor (AHR) target genes such as the best characterized, cytochrome P450 1A1 (CYP1A1) has not been known. Therefore the aim of this study was to explore how cellular redox… read more here.
Keywords: gssg; p450 1a1; hydrocarbon receptor; aryl hydrocarbon ... See more keywords
Nicotinamide prevents sweet beverage‐induced hepatic steatosis in rats by regulating the G6PD, NADPH/NADP+ and GSH/GSSG ratios and reducing oxidative and inflammatory stress
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2017.10.048
Abstract: Abstract The disruption of redox state homeostasis, the overexpression of lipogenic transcription factors and enzymes, and the increase in lipogenic precursors induced by sweetened beverages are determinants of the development of nonalcoholic fatty liver disease.… read more here.
Keywords: g6pd; hepatic steatosis; gsh gssg; steatosis ... See more keywords
Facile and sensitive measurement of GSH/GSSG in cells by surface-enhanced Raman spectroscopy.
Sign Up to like & getrecommendations! Published in 2021 at "Talanta"
DOI: 10.1016/j.talanta.2020.121852
Abstract: Reduced glutathione (GSH) and the oxidized glutathione (GSSG) are well-known biomolecules in the main constituents of intracellular redox homeostasis system. A rapid, accurate measurement of cellular GSH and GSSG is quite needed in investigating important… read more here.
Keywords: surface enhanced; gsh; measurement; gsh gssg ... See more keywords
Capsaicin Alleviates the Deteriorative Mitochondrial Function by Upregulating 14-3-3η in Anoxic or Anoxic/Reoxygenated Cardiomyocytes
Sign Up to like & getrecommendations! Published in 2020 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2020/1750289
Abstract: Reactive oxygen species (ROS) are byproducts of a defective electron transport chain (ETC). The redox couples, GSH/GSSG and NAD+/NADH, play an essential role in physiology as internal defenses against excessive ROS generation by facilitating intracellular/mitochondrial… read more here.
Keywords: nad nadh; complex iii; mitochondrial function; redox ... See more keywords
Omega-Class Glutathione Transferases Protect DNA from Oxidative Stress in Pathogenic Helminth Reproductive Cells
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DOI: 10.3390/antiox12030560
Abstract: Pathogenic helminths have evolved mechanisms to preserve reproductive function while surviving long-term in the host via robust protective responses. A protective role of antioxidant enzymes in preventing DNA degradation has long been proposed, but little… read more here.
Keywords: stress; dna; oxidative stress; gsh gssg ... See more keywords