GSH‐Responsive Mn2+ Burst Nanoboxes as Mitophagy Intervention Agents Augment Ferroptosis and Chemoimmunotherapy in Triple‐Negative Breast Cancer
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202500491
Abstract: Chemoimmunotherapy is recognized as a promising approach for treating cancer patients. However, the overall therapeutic efficacy of treatments for triple‐negative breast cancer (TNBC) is compromised by several factors, including its highly immunosuppressive tumor microenvironment, the… read more here.
Keywords: cancer; breast cancer; negative breast; gsh responsive ... See more keywords
Synthesis of Glutathione (GSH)-Responsive Amphiphilic Duplexes and their Application in Gene Delivery.
Sign Up to like & getrecommendations! Published in 2019 at "ChemPlusChem"
DOI: 10.1002/cplu.201900295
Abstract: Oligoamide molecular strands with hydrogen-bonding sequences DADDAD and guanidine (O-1) or 1,5,9-triazacyclododecane ([12]aneN3 ; O-2) side chains and oligoamides with hydrogen-bonding sequences ADAADA and octyl moieties (O-3), were synthesized. Two duplexes (D-1 and D-2) were… read more here.
Keywords: synthesis glutathione; glutathione gsh; gsh responsive; responsive amphiphilic ... See more keywords
Glutathione responsive polymers and their application in drug delivery systems
Sign Up to like & getrecommendations! Published in 2017 at "Polymer Chemistry"
DOI: 10.1039/c6py01365a
Abstract: Materials which respond to biological cues are the subject of intense research interest due to their possible application in smart drug delivery vehicles. In particular, novel polymers which respond to biochemical differences between the extra-and… read more here.
Keywords: responsive polymers; drug delivery; gsh responsive; delivery ... See more keywords
GSH-responsive magnetic mesoporous silica nanoparticles for efficient controlled drug delivery in tumor cells
Sign Up to like & getrecommendations! Published in 2024 at "AIP Advances"
DOI: 10.1063/5.0238257
Abstract: In this study, glutathione (GSH)-responsive magnetic mesoporous silica nanoparticles grafted by disulfide organosilicon (SMNPs) were synthesized, characterized, and evaluated as controlled drug carriers. The nanoparticles exhibited consistent dispersion, considerable drug-loading capacity, and high saturation magnetization.… read more here.
Keywords: mesoporous silica; responsive magnetic; magnetic mesoporous; gsh responsive ... See more keywords
Perfluorocarbon Nanodroplets for Dual Delivery with Ultrasound/GSH-Responsive Release of Model Drug and Passive Release of Nitric Oxide
Sign Up to like & getrecommendations! Published in 2022 at "Polymers"
DOI: 10.3390/polym14112240
Abstract: Nitric oxide (NO) plays a critical role as an important signaling molecule for a variety of biological functions, particularly inhibiting cell proliferation or killing target pathogens. To deliver active radical NO gaseous molecule whose half-life… read more here.
Keywords: gsh; nitric oxide; gsh responsive; release ... See more keywords