LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "gsk bgr" as a keyword



Photo by mykjohnson from unsplash

Diabetes mellitus and Alzheimer’s disease: GSK-3β as a potential link

Sign Up to like & get
recommendations! Published in 2018 at "Behavioural Brain Research"

DOI: 10.1016/j.bbr.2017.11.015

Abstract: HIGHLIGHTSGSK‐3&bgr; is involved in the physiological and pathological progress of DM and AD respectively.In DM, GSK‐3&bgr; is one of the key factors leading to insulin deficiency and insulin resistance.In AD, GSK‐3&bgr; plays an important role… read more here.

Keywords: insulin; gsk bgr; bgr; potential link ... See more keywords
Photo by markusspiske from unsplash

Remote limb ischemic post conditioning during early reperfusion alleviates cerebral ischemic reperfusion injury via GSK‐3&bgr;/CREB/ BDNF pathway

Sign Up to like & get
recommendations! Published in 2017 at "European Journal of Pharmacology"

DOI: 10.1016/j.ejphar.2017.03.028

Abstract: Abstract Remote limb ischemic post conditioning (RIPOC) has been reported to attenuate cerebral ischemic reperfusion (I/R) injury, while the molecular mechanisms remain elusive. Various studies have highlighted the involvement of glycogen synthase kinase (GSK‐3&bgr;) in… read more here.

Keywords: reperfusion; gsk bgr; injury; creb bdnf ... See more keywords
Photo by myriamzilles from unsplash

Nimodipine attenuates tau phosphorylation at Ser396 via miR‐132/GSK‐3&bgr; pathway in chronic cerebral hypoperfusion rats

Sign Up to like & get
recommendations! Published in 2018 at "European Journal of Pharmacology"

DOI: 10.1016/j.ejphar.2017.10.027

Abstract: ABSTRACT Chronic cerebral hypofusion (CCH) promotes hyperphosphorylation of tau proteins, a key neuropathological trait that reflects neurodegenerative disorders. Nimodipine, an L‐type calcium channel antagonist, has been reported to show neuroprotective effects. In this study, we… read more here.

Keywords: tau phosphorylation; gsk bgr; phosphorylation ser396; mir 132 ... See more keywords

Inhibition of GSK‐3&bgr; alleviates cerebral ischemia/reperfusion injury in rats by suppressing NLRP3 inflammasome activation through autophagy

Sign Up to like & get
recommendations! Published in 2019 at "International Immunopharmacology"

DOI: 10.1016/j.intimp.2018.12.042

Abstract: ABSTRACT The nod‐like receptor protein 3 (NLRP3) inflammasome has a critical role in cerebral ischemic injury, and autophagy is related to activation of the inflammasome under oxidative stress conditions. However, it is unclear how NLRP3… read more here.

Keywords: bgr; activation; nlrp3 inflammasome; gsk bgr ... See more keywords