Deletion of Schizophrenia Susceptibility Gene Ulk4 Leads to Abnormal Cognitive Behaviors via Akt-GSK-3 Signaling Pathway in Mice.
Sign Up to like & getrecommendations! Published in 2022 at "Schizophrenia bulletin"
DOI: 10.1093/schbul/sbac040
Abstract: OBJECTIVES Despite of strenuous research in the past decades, the etiology of schizophrenia (SCZ) still remains incredibly controversial. Previous genetic analysis has uncovered a close association of Unc-51 like kinase 4 (ULK4), a family member… read more here.
Keywords: cko mice; gsk signaling; signaling pathway; akt gsk ... See more keywords
Inhibition of RIP1-RIP3-mediated necroptosis attenuates renal fibrosis via Wnt3α/β-catenin/GSK-3β signaling in unilateral ureteral obstruction
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DOI: 10.1371/journal.pone.0274116
Abstract: Renal fibrosis represents the final common outcome of chronic kidney disease of virtually any etiology. However, the mechanism underlying the evolution of renal fibrosis remains to be addressed. This study sought to clarify whether RIP1-RIP3-mediated… read more here.
Keywords: catenin gsk; gsk signaling; renal fibrosis; wnt3 catenin ... See more keywords
Regulation of Autophagy by the Glycogen Synthase Kinase-3 (GSK-3) Signaling Pathway
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23031709
Abstract: Autophagy is a vital cellular mechanism that benefits cellular maintenance and survival during cell stress. It can eliminate damaged or long-lived organelles and improperly folded proteins to maintain cellular homeostasis, development, and differentiation. Impaired autophagy… read more here.
Keywords: gsk signaling; signaling pathway; regulation autophagy; kinase ... See more keywords