Salvianolic acid B attenuates oxidative stress-induced injuries in enterocytes by activating Akt/GSK3β signaling and preserving mitochondrial function.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2021.174408
Abstract: The cellular and tissue damage induced by oxidative stress (OS) contribute to a variety of human diseases, which include gastrointestinal diseases. Salvianolic acid B (Sal B), which is a natural polyphenolic acid in Salvia miltiorrhiza,… read more here.
Keywords: gsk3 signaling; oxidative stress; salvianolic acid; stress induced ... See more keywords
B02 The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Thoracic Oncology"
DOI: 10.1016/j.jtho.2019.12.071
Abstract: Author(s): Momcilovic, M; Lee, JT; Braas, D; Graeber, TG; Parlati, F; Demo, S; Li, R; Gricowski, M; Shuman, R; Ibarra, J; Fridman, D; St.John, M; Bernthal, N; Federman, N; Yanagawa, J; Dubinett, SM; Sadeghi, S;… read more here.
Keywords: b02 gsk3; adaptive glutamine; gsk3 signaling; signaling axis ... See more keywords
Dose-dependent effects of isoflurane on TrkB and GSK3β signaling: importance of burst suppression pattern
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience letters"
DOI: 10.1016/j.neulet.2018.11.018
Abstract: OBJECTIVES Deep burst-suppressing isoflurane anesthesia regulates signaling pathways connected with antidepressant responses in the rodent brain: activation of TrkB neurotrophin receptor and inhibition of GSK3β kinase (glycogen synthase kinase 3β). The main objective of this… read more here.
Keywords: gsk3; gsk3 signaling; burst suppression; trkb gsk3 ... See more keywords
Momordica charantia Exosome-Like Nanoparticles Exert Neuroprotective Effects Against Ischemic Brain Injury via Inhibiting Matrix Metalloproteinase 9 and Activating the AKT/GSK3β Signaling Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.908830
Abstract: Plant exosome-like nanoparticles (ELNs) have shown great potential in treating tumor and inflammatory diseases, but the neuroprotective effect of plant ELNs remains unknown. In the present study, we isolated and characterized novel ELNs from Momordica… read more here.
Keywords: gsk3 signaling; signaling pathway; expression; akt gsk3 ... See more keywords
Inhibition of miR-98-5p promotes high glucose-induced suppression of preosteoblast proliferation and differentiation via the activation of the PI3K/AKT/GSK3β signaling pathway by targeting BMP2
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Medicine Reports"
DOI: 10.3892/mmr.2022.12808
Abstract: Osteoporosis (OP) is a bone metabolic disease, in which low bone mass and the microarchitectural deterioration of bone tissue contribute to the fragility of bones and increase the risk of fracture. The aim of the… read more here.
Keywords: pi3k akt; gsk3 signaling; signaling pathway; akt gsk3 ... See more keywords