Articles with "gsk525762" as a keyword



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Abstract OT3-06-07: A phase I/II dose escalation and expansion study to investigate the safety, pharmacokinetics, pharmacodynamics and clinical activity of GSK525762 in combination with fulvestrant in subjects with ER+ breast cancer

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Published in 2018 at "Cancer Research"

DOI: 10.1158/1538-7445.sabcs17-ot3-06-07

Abstract: Background: Advanced or metastatic ER+BC (estrogen receptor positive breast cancer) is an incurable illness that will prove fatal for most afflicted women. Current standards of care include endocrine, targeted, and chemotherapy. Preclinical data suggest that… read more here.

Keywords: combination; phase; breast cancer; cancer ... See more keywords