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   Articles with "gsn" as a keyword



Oral administration of alcalase potato protein hydrolysate‐APPH attenuates high fat diet‐induced cardiac complications via TGF‐β/GSN axis in aging rats

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recommendations! Published in 2019 at "Environmental Toxicology"

DOI: 10.1002/tox.22651

Abstract: Consumption of high fat diet (HFD) is associated with increased cardiovascular risk factors among elderly people. Aging and obesity induced‐cardiac remodeling includes hypertrophy and fibrosis. Gelsolin (GSN) induces cardiac hypertrophy and TGF‐β, a key cytokine,… read more here.

Keywords: induced cardiac; tgf gsn; tgf; hypertrophy ... See more keywords

Interpretable machine learning uncovers epithelial transcriptional rewiring and a role for Gelsolin in COPD

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recommendations! Published in 2024 at "JCI Insight"

DOI: 10.1172/jci.insight.180239

Abstract: Transcriptomic analyses have advanced the understanding of complex disease pathophysiology including chronic obstructive pulmonary disease (COPD). However, identifying relevant biologic causative factors has been limited by the integration of high dimensionality data. COPD is characterized… read more here.

Keywords: gsn; copd; machine learning; gelsolin ... See more keywords

Skin melanoma cells produce diverse gelsolin (GSN) isoforms, which play non-redundant roles in cells’ proliferation and motility

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recommendations! Published in 2025 at "Cancer Cell International"

DOI: 10.1186/s12935-025-03876-x

Abstract: Skin melanoma is a malignant tumor that becomes increasingly difficult to treat when diagnosed late. Previously, we demonstrated that high levels of gelsolin (GSN) correlate with the advanced stages of cutaneous melanoma. GSN can be… read more here.

Keywords: gsn; gsn isoforms; skin melanoma; melanoma ... See more keywords

Disentangling signal and noise in neural responses through generative modeling

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recommendations! Published in 2025 at "PLOS Computational Biology"

DOI: 10.1371/journal.pcbi.1012092

Abstract: Measurements of neural responses to identically repeated experimental events often exhibit large amounts of variability. This noise is distinct from signal, operationally defined as the average expected response across repeated trials for each given event.… read more here.

Keywords: gsn; noise; disentangling signal; generative modeling ... See more keywords

Gelsolin Can Be a Prognostic Biomarker and Correlated with Immune Infiltrates in Gastric Cancer

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recommendations! Published in 2022 at "International Journal of General Medicine"

DOI: 10.2147/ijgm.s339940

Abstract: Background Gelsolin (GSN) is the most widely expressed actin-severing protein in humans, which could regulate cell morphology, differentiation, movement and apoptosis. This study aims to explore the GSN as a prognostic biomarker of stomach adenocarcinoma… read more here.

Keywords: expression; prognostic biomarker; gsn; gastric cancer ... See more keywords
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Fusion of the High-mobility Group AT-Hook 2 (HMGA2) and the Gelsolin (GSN) Genes in Lipomas With t(9;12)(q33;q14) Chromosomal Translocation

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recommendations! Published in 2023 at "In Vivo"

DOI: 10.21873/invivo.13110

Abstract: Background/Aim: Lipomas are benign tumors composed of mature fat cells. They are common soft tissue tumors that often carry chromosome aberrations involving 12q14 resulting in rearrangements, deregulation, and generation of chimeras of the high-mobility group… read more here.

Keywords: group hook; q33 q14; mobility group; hmga2 ... See more keywords

Preparation and Evaluation of Liposomes and Niosomes Containing Total Ginsenosides for Anti-Photoaging Therapy

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recommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"

DOI: 10.3389/fbioe.2022.874827

Abstract: Ginsenosides are the principal bioactive compounds of ginseng. Total ginsenosides (GS) contain a variety of saponin monomers, which have potent anti-photoaging activity and improve the skin barrier function. To enhance the efficiency of GS transdermal… read more here.

Keywords: gsn; skin; total ginsenosides; gsl gsn ... See more keywords

Production and Secretion of Gelsolin by Both Human Macrophage- and Fibroblast-like Synoviocytes and GSN Modulation in the Synovial Fluid of Patients with Various Forms of Arthritis

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recommendations! Published in 2022 at "Biomedicines"

DOI: 10.3390/biomedicines10030723

Abstract: Gelsolin (GSN) is an actin-binding protein involved in cell formation, metabolism and wound closure processes. Since this protein is known to play a role in arthritis, here we investigate how the synovial membrane with its… read more here.

Keywords: like synoviocytes; gsn; fibroblast like; various forms ... See more keywords