Maternal intake of grape seed procyanidins during lactation induces insulin resistance and an adiponectin resistance-like phenotype in rat offspring
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-12597-9
Abstract: Previously, we demonstrated that a grape seed procyanidin extract (GSPE) supplementation in pregnant and lactating rats exerted both healthy and deleterious programming effects on their offspring. Here, we evaluated whether the administration of GSPE during… read more here.
Keywords: seed; resistance; adiponectin; insulin resistance ... See more keywords
Grape seed procyanidin extract inhibits adipogenesis and stimulates lipolysis of porcine adipocytes in vitro.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of animal science"
DOI: 10.1093/jas/sky158
Abstract: The objective of this article was to evaluate in vitro effect of grape seed procyanidin extract (GSPE) on differentiation, proliferation, and lipolysis of porcine adipocytes, providing a molecular basis for the use of GSPE in… read more here.
Keywords: seed; procyanidin extract; porcine; seed procyanidin ... See more keywords
Proanthocyanidins Antagonize Arsenic-Induced Oxidative Damage and Promote Arsenic Methylation through Activation of the Nrf2 Signaling Pathway
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DOI: 10.1155/2019/8549035
Abstract: Purpose To investigate the effects of grape seed proanthocyanidin extract (GSPE) on oxidative damage and arsenic (As) methylation and to clarify the role of Nrf2 in the process. Methods L-02 cells were treated with arsenic… read more here.
Keywords: arsenic methylation; methylation; oxidative damage; group ... See more keywords
Grape Seeds Proanthocyanidins: An Overview of In Vivo Bioactivity in Animal Models
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DOI: 10.3390/nu11102435
Abstract: Over the last decade, proanthocyanidins (PACs) are attracting attention not only from the food industry but also from public health organizations due to their health benefits. It is well-known that grapes are a good source… read more here.
Keywords: bioactivity; grape seeds; overview vivo; proanthocyanidins overview ... See more keywords
Intestinal Morphometric Changes Induced by a Western-Style Diet in Wistar Rats and GSPE Counter-Regulatory Effect
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DOI: 10.3390/nu14132608
Abstract: Western-style diet is an obesogenic diet for rodents and humans due to its content of saturated fat and refined sugars, mainly sucrose and, in consequence, sucrose-derived fructose. This type of diets relates with intestinal disturbances… read more here.
Keywords: style diet; changes induced; caf; western style ... See more keywords