Génotypes nuls de deux glutathion S-transférases (GSTM1 ; GSTT1) et prédisposition à l’épilepsie
Sign Up to like & getrecommendations! Published in 2018 at "Revue Neurologique"
DOI: 10.1016/j.neurol.2018.01.051
Abstract: Introduction Les glutathion S-transferases (GSTs) sont des enzymes de la phase II du metabolisme, impliquees dans la detoxification d’un grand nombre d’especes reactives de l’oxygene, y compris ceux derives de la dopamine et d’autres catecholamines.… read more here.
Keywords: chez; genotype nul; epilepsie; glutathion ... See more keywords
GSTM1 and GSTT1 null genotype increase the risk of hepatocellular carcinoma: evidence based on 46 studies
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Cell International"
DOI: 10.1186/s12935-019-0792-3
Abstract: BackgroundIt is well known that hepatocellular carcinoma (HCC) has been one of the most life-threatening diseases all over the world. Plenty of internal and extrinsic factors have been proven to be related to HCC, such… read more here.
Keywords: gstt1 null; risk; gstm1 gstt1; null genotypes ... See more keywords
Influence of GSTM1, GSTT1, and GSTP1 genetic polymorphisms on disorders in transplant patients: a systematic review
Sign Up to like & getrecommendations! Published in 2021 at "Drug Metabolism and Personalized Therapy"
DOI: 10.1515/dmpt-2021-0165
Abstract: Abstract The glutathione-S-transferase (GST) enzymes are phase II isoenzymes responsible for protection against free radicals and xenobiotics. Since these proteins are described as polymorphic, polymorphisms in genes that encode them may alter enzymatic function and… read more here.
Keywords: influence; disorders transplant; gstm1 gstt1; systematic review ... See more keywords
GSTM1 and GSTT1 polymorphisms are associated with increased bladder cancer risk: Evidence from updated meta-analysis
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.13702
Abstract: Background Previous studies have indicated association between GSTM1 and GSTT1 gene polymorphisms and bladder cancer susceptibility, but the results have been inconclusive. Here, we performed a meta-analysis to investigate the association between GSTM1/GSTT1 deletion polymorphisms… read more here.
Keywords: bladder cancer; risk; bladder; gstm1 gstt1 ... See more keywords
Mixed exposure effect of seminal metals on semen quality, mediation of total antioxidant capacity, and moderation of GSTM1/GSTT1 gene deletion in Chinese reproductive-aged men.
Sign Up to like & getrecommendations! Published in 2023 at "Environmental research"
DOI: 10.2139/ssrn.4379446
Abstract: BACKGROUND The effects of metal exposure on semen quality and the role of oxidative damage in this process remain unclear. METHODS We recruited 825 Chinese male volunteers, and 12 seminal metals (Mn, Cu, Zn, Se,… read more here.
Keywords: semen quality; gstt1; seminal metals; gstm1 gstt1 ... See more keywords
GENETIC POLYMORPHISMS AND THE RISK OF LUNG CANCER IN TUNNEL WORKERS IN RIO DE JANEIRO, BRAZIL
Sign Up to like & getrecommendations! Published in 2017 at "Artificial Intelligence Review"
DOI: 10.2495/air170061
Abstract: Individual susceptibility to chemically induced cancer may be partly explained by genetic differences in the activation and detoxification of procarcinogens. Numerous polymorphisms of metabolism genes have been identified and their role in individual susceptibility to… read more here.
Keywords: cancer; risk lung; gstm1 gstt1; lung cancer ... See more keywords
The Leucocyte Telomere Length, GSTM1 and GSTT1 Null Genotypes and the Risk of Chronic Obstructive Pulmonary Disease
Sign Up to like & getrecommendations! Published in 2022 at "Current Issues in Molecular Biology"
DOI: 10.3390/cimb44080257
Abstract: Simple Summary Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation and oxidative stress, both in the airways and blood, and in other organs. Elevated oxidative stress and inflammation have been reported to affect… read more here.
Keywords: null genotype; copd; gstm1 gstt1;
Do Polymorphisms of the TERT, GSTM1, and GSTT1 Genes Increase Laryngeal Cancer Susceptibility in Smokers of Romanian Descent?
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DOI: 10.3390/medicina58081106
Abstract: Background and Objectives: The aim of this study was to investigate the association between smoking status and single-nucleotide polymorphism in candidate genes that had a known association with smoking-related tumors in previous studies and to… read more here.
Keywords: laryngeal cancer; romanian descent; risk; gstm1 gstt1 ... See more keywords
Assessment of the Two-Glutathione S-Transferase Genotypes GSTM1 and GSTT1 Polymorphism Frequencies in Epithelial Ovarian Cancer in Nasiriya Province
Sign Up to like & getrecommendations! Published in 2020 at "Medico-Legal Update"
DOI: 10.37506/mlu.v20i4.2088
Abstract: The family of glutathione S-transferases (GSTs) is composed of multiple isozymes with significant evidenceof functional polymorphic variation. Glutathione S-transferase GSTM1 and GSTT1 are members of theGST family, is responsible for metabolism of xenobiotics and carcinogens.… read more here.
Keywords: ovarian cancer; gstm1 gstt1; cancer; glutathione transferase ... See more keywords
Desloratadine Efficacy in Relation to GSTM1 and GSTT1 Polymorphic Genes in Chronic Spontaneous Urticaria
Sign Up to like & getrecommendations! Published in 2022 at "Indian Journal of Dermatology"
DOI: 10.4103/ijd.ijd_546_17
Abstract: Background: The etiopathogeny of chronic spontaneous urticaria (CSU) is not well defined. Allelism in glutathione S-transferase GSTM1 and GSTT1 has been suggested as a risk factor. Desloratadine is the first-line treatment for this disease. Objective:… read more here.
Keywords: desloratadine; efficacy; treatment; gstm1 ... See more keywords