Molecular characterization of a novel GSTO2 of Fasciola hepatica and its roles in modulating murine macrophages
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DOI: 10.1051/parasite/2022016
Abstract: Fascioliasis is an important zoonotic helminthic disease caused by Fasciola hepatica and poses a serious threat to global public health. To evade the immune response of its host (humans or animals), F. hepatica secretes various… read more here.
Keywords: fasciola hepatica; hepatica; rgsto2 protein; murine macrophages ... See more keywords
Loss of GSTO2 contributes to cell growth and mitochondria function via the p38 signaling in lung squamous cell carcinoma.
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DOI: 10.1111/cas.15189
Abstract: Glutathione S-transferase omega 2 (GSTO2) lacks any appreciable GST activity, but it exhibits thioltransferase activity. The significance of GSTO2 in lung function has been reported; however, the precise expression and molecular function of GSTO2 in… read more here.
Keywords: cell; lscc; expression; transfected cells ... See more keywords
Genome-wide splicing QTL analysis identifies causal risk variants for non-small cell lung cancer.
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DOI: 10.1158/0008-5472.can-22-3184
Abstract: Alternative RNA splicing is an essential mechanism linking genetic variation to human diseases. While the signals from genome-wide association studies(GWAS) have been linked to expression quantitative trait loci(eQTLs) in previous studies,further work is needed to… read more here.
Keywords: cell; non small; genome wide; risk ... See more keywords