Association between glutathione S‐transferase gene M1 and T1 polymorphisms and chronic obstructive pulmonary disease risk: A meta‐analysis
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DOI: 10.1111/cge.13373
Abstract: Chronic obstructive pulmonary disease (COPD) is a severe lung disease characterized by long‐term breathing problems. A series of studies have indicated that the glutathione S‐transferase genes M1 and T1 are associated with COPD susceptibility; however,… read more here.
Keywords: analysis; disease; association; copd ... See more keywords
Influence of functional variants Asp312Asn and Lys751Gln of Xeroderma Pigmentosum Group D (XPD) and Glutathione S‐transferase Mu 1 (GSTM1) and Theta 1 (GSTT1) genes on cutaneous melanoma susceptibility and prognosis
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DOI: 10.1111/exd.13914
Abstract: We aimed to evaluate whether variants in repair (XPD Asp312Asn, XPD Lys751Gln) and detoxification (GSTM1, GSTT1) genes alter risk, clinicopathological aspects and survival of cutaneous melanoma (CM). Genotyping was performed in 229 CM patients and… read more here.
Keywords: gstm1; plus gstt1; cutaneous melanoma; gstt1 ... See more keywords
Influence of chemotherapeutic drug-related gene polymorphisms on toxicity and survival of early breast cancer patients receiving adjuvant chemotherapy
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DOI: 10.1186/s12885-017-3483-2
Abstract: BackgroundWe investigated whether GSTT1 (“null” allele), GSTM1 (“null”allele), GSTP1 (A313G), RFC1 (G80A), MTHFR (C677T), TS (2R/3R) polymorphisms were associated with toxicity and survival in patients with early breast cancer (EBC) treated with adjuvant chemotherapy (CT).MethodsThis… read more here.
Keywords: early breast; genotype; toxicity survival; cancer ... See more keywords
GSTM1 and GSTT1 null genotype increase the risk of hepatocellular carcinoma: evidence based on 46 studies
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DOI: 10.1186/s12935-019-0792-3
Abstract: BackgroundIt is well known that hepatocellular carcinoma (HCC) has been one of the most life-threatening diseases all over the world. Plenty of internal and extrinsic factors have been proven to be related to HCC, such… read more here.
Keywords: gstt1 null; risk; gstm1 gstt1; null genotypes ... See more keywords