Antiviral Activity and Resistance Analysis of NS3/4A Protease Inhibitor Grazoprevir and NS5A Inhibitor Elbasvir in Hepatitis C Virus GT4 Replicons
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DOI: 10.1128/aac.00363-17
Abstract: ABSTRACT Although genotype 4 (GT4)-infected patients represent a minor overall percentage of the global hepatitis C virus (HCV)-infected population, the high prevalence of the genotype in specific geographic regions coupled with substantial sequence diversity makes… read more here.
Keywords: inhibitor; ns3 protease; elbasvir; gt4 ... See more keywords
Differences in Growth Properties among Two Human Cytomegalovirus Glycoprotein O Genotypes
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DOI: 10.3389/fmicb.2017.01609
Abstract: Glycoprotein O (gO) of the human cytomegalovirus (HCMV) is the critical subunit of the envelope trimer gH/gL/gO as it interacts with platelet-derived growth factor alpha receptor upon fibroblast entry, and triggers gB-mediated fusion for fibroblast… read more here.
Keywords: free infectivity; cell free; gt4; human cytomegalovirus ... See more keywords