Consistent hypersocial behavior in mice carrying a deletion of Gtf2i but no evidence of hyposocial behavior with Gtf2i duplication: Implications for Williams–Beuren syndrome and autism spectrum disorder
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DOI: 10.1002/brb3.895
Abstract: Williams–Beuren syndrome (WBS) is a developmental disorder caused by hemizygous deletion of human chromosome 7q11.23. Hypersocial behavior is one symptom of WBS and contrasts with hyposociality observed in autism spectrum disorder (ASD). Interestingly, duplications of… read more here.
Keywords: beuren syndrome; hypersocial behavior; disorder; gtf2i ... See more keywords
Primary Driver Mutations in GTF2I Specific to the Development of Thymomas
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DOI: 10.3390/cancers12082032
Abstract: Thymomas are rare mediastinal tumors that are difficult to treat and pose a major public health concern. Identifying mutations in target genes is vital for the development of novel therapeutic strategies. Type A thymomas possess… read more here.
Keywords: mutations gtf2i; type thymomas; mutant gtf2i; gtf2i ... See more keywords