Articles with "gtn" as a keyword



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Crack initiation and propagation in small-scale yielding using a nonlocal GTN model

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Published in 2020 at "International Journal of Plasticity"

DOI: 10.1016/j.ijplas.2020.102701

Abstract: Abstract This study aims at investigating a non-local Gurson-Tvergaard-Needleman (GTN) ductile damage model at finite strains within the framework of small-scale yielding. This model solves the problems of spurious strain localization and volumetric locking. The… read more here.

Keywords: crack initiation; gtn; model; small scale ... See more keywords
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Immune cell composition in the endometrium of patients with a complete molar pregnancy: Effects on outcome.

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Published in 2020 at "Gynecologic oncology"

DOI: 10.1016/j.ygyno.2020.11.005

Abstract: OBJECTIVE In 15% of patients with complete hydatidiform mole (CHM), disease progresses to post-molar gestational trophoblastic neoplasia (GTN) after curettage. Tumor infiltrating lymphocytes (TILs) are essential in overcoming disease in many tumors. Infiltrating lymphocyte composition… read more here.

Keywords: patients chm; gtn; density; nkt like ... See more keywords
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Current chemotherapeutic options for the treatment of gestational trophoblastic disease

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Published in 2022 at "Expert Opinion on Pharmacotherapy"

DOI: 10.1080/14656566.2022.2150075

Abstract: ABSTRACT Introduction Gestational trophoblastic neoplasia (GTN) is a rare tumor that arises from trophoblastic tissues with high remission rates after chemotherapy treatment. GTN can develop from any gestational events, such as miscarriage, ectopic pregnancy, and… read more here.

Keywords: disease; gestational trophoblastic; gtn; treatment ... See more keywords
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Transdermal delivery of glyceryl trinitrate: clinical applications in acute stroke

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Published in 2020 at "Expert Opinion on Drug Delivery"

DOI: 10.1080/17425247.2020.1716727

Abstract: ABSTRACT Introduction Glyceryl trinitrate (GTN), a nitric oxide donor, is a candidate treatment for the management of acute stroke with hemodynamic and potential reperfusion and neuroprotective effects. Areas covered Here we discuss the evidence to… read more here.

Keywords: glyceryl trinitrate; delivery; gtn; acute stroke ... See more keywords
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The Effect of Vitamin C on Nitroglycerin Mediated Vasodilation in Individuals with and without the Aldehyde Dehydrogenase 2 polymorphism.

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Published in 2023 at "British journal of clinical pharmacology"

DOI: 10.1111/bcp.15755

Abstract: AIM To mediate its pharmacodynamic effects, glyceryl trinitrate (GTN) requires bioactivation, by which it releases nitric oxide or a nitric oxide moiety. The exact mechanism of GTN bioactivation remains uncertain. The mitochondrial aldehyde dehydrogenase (ALDH-2)… read more here.

Keywords: polymorphism; effect; aldehyde dehydrogenase; bioactivation ... See more keywords
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Sublingual Nitrates for Patients as a Default in the Post-ACS Discharge Pack: Is It Time for a Rethink?

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Published in 2022 at "Circulation"

DOI: 10.1161/circulationaha.121.058008

Abstract: The current era of management for coronary artery disease and acute coronary syndromes (ACS) is guided by high-level evidence from large-scale, prospective clinical trials. Although certain therapies such as early invasive therapy, dual antiplatelet therapy,… read more here.

Keywords: cardiology; therapy; elevation; acs ... See more keywords
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Nitric Oxide Is the Cause of Nitroglycerin Tolerance: Providing an Old Dog New Tricks for Acute Heart Failure

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Published in 2022 at "Journal of Cardiovascular Pharmacology and Therapeutics"

DOI: 10.1177/10742484221086091

Abstract: Our paper highlights the past 50 years of research focusing solely on tolerance involving nitroglycerin (glyceryl trinitrate, GTN). It also identifies and discusses inconsistencies in previous mechanistic explanations that have failed to provide a way… read more here.

Keywords: gtn; heart failure; tolerance; nitric oxide ... See more keywords
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Neutrophil/lymphocyte ratio and other blood cell component counts are not associated with the development of postmolar gestational trophoblastic neoplasia

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Published in 2022 at "PLOS ONE"

DOI: 10.1371/journal.pone.0277892

Abstract: Objective To relate preevacuation platelet count and leukogram findings, especially neutrophil/lymphocyte ratios (NLR) and platelet/lymphocyte ratios with the occurrence of gestational trophoblastic neoplasia (GTN) after complete hydatidiform mole (CHM) among Brazilian women. Methods Retrospective cohort… read more here.

Keywords: trophoblastic neoplasia; postmolar gtn; gestational trophoblastic; gtn ... See more keywords
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Clinical Features of Gestational Trophoblastic Disease in Aged Women in South Vietnam

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Published in 2023 at "Yonsei Medical Journal"

DOI: 10.3349/ymj.2022.0241

Abstract: Purpose This study aimed to determine the occurrence rate of gestational trophoblastic neoplasia (GTN) and its related factors in aged women with hydatidiform mole (HM) in Tu Du Hospital, Vietnam. Materials and Methods This retrospective… read more here.

Keywords: gtn rate; aged women; gestational trophoblastic; group ... See more keywords
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Prognostic Power of Pulmonary Arterial Compliance Is Boosted by a Hemodynamic Unloading Test With Glyceryl Trinitrate in Heart Failure Patients With Post-capillary Pulmonary Hypertension

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Published in 2022 at "Frontiers in Cardiovascular Medicine"

DOI: 10.3389/fcvm.2022.838898

Abstract: Background Pulmonary hypertension (PH) is an established risk factor in patients with heart failure (HF). However, right heart catheterisation (RHC) and vasoreactivity testing (VRT) are not routinely recommended in these patients. Methods The primary objective… read more here.

Keywords: patients post; post capillary; gtn; heart failure ... See more keywords
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Current Evidence on Immunotherapy for Gestational Trophoblastic Neoplasia (GTN)

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers14112782

Abstract: Simple Summary Gestational trophoblastic neoplasia (GTN) is a rare tumor group that arises from the malignant transformation of placental tissue. Based on the evaluation of International Federation of Gynecology and Obstetrics (FIGO) anatomic staging and… read more here.

Keywords: trophoblastic neoplasia; gestational trophoblastic; neoplasia gtn; gtn ... See more keywords