Abstract PR01: Structural plasticity of KRAS oncogenic mutants – A case of misleading conclusions from GTP analogues
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DOI: 10.1158/1557-3125.ras23-pr01
Abstract: RAS mutations occur in approximately 20% of human cancers including the majority of pancreatic ductal adenocarcinoma (PDAC), half of colorectal cancers, and a third of all lung cancers. In cases of oncogenic activating RAS mutations,… read more here.
Keywords: structural plasticity; state; gtp bound; state state ... See more keywords