GTP-cyclohydrolase deficiency induced peripheral and deep microcirculation dysfunction with age.
Sign Up to like & getrecommendations! Published in 2020 at "Microvascular research"
DOI: 10.1016/j.mvr.2020.104078
Abstract: The present study assessed the impact of impaired tetrahydrobiopterin (BH4) production on vasoreactivity from conduit and small arteries along the vascular tree as seen during aging. For this purpose, the mutant hyperphenylalaninemic mouse (hph-1) was… read more here.
Keywords: gtp cyclohydrolase; hph; mice; middle aged ... See more keywords
Identification and Functional Analysis of GTP Cyclohydrolase II in Candida glabrata in Response to Nitrosative Stress
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.825121
Abstract: Reactive nitrogen species (RNS) are signal molecules involved in various biological events; however, excess levels of RNS cause nitrosative stress, leading to cell death and/or cellular dysfunction. During the process of infection, pathogens are exposed… read more here.
Keywords: glabrata; stress resistance; stress; gtp cyclohydrolase ... See more keywords