The Small GTPase ARF6 Activates PI3K in Melanoma to Induce a Prometastatic State.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer research"
DOI: 10.1158/0008-5472.can-18-3026
Abstract: Melanoma has an unusual capacity to spread in early-stage disease, prompting aggressive clinical intervention in very thin primary tumors. Despite these proactive efforts, patients with low-risk, low-stage disease can still develop metastasis, indicating the presence… read more here.
Keywords: activation; metastasis; melanoma; arf6 ... See more keywords
The small GTPase ARF6 regulates GABAergic synapse development
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DOI: 10.1186/s13041-019-0543-3
Abstract: ADP ribosylation factors (ARFs) are a family of small GTPases composed of six members (ARF1–6) that control various cellular functions, including membrane trafficking and actin cytoskeletal rearrangement, in eukaryotic cells. Among them, ARF1 and ARF6… read more here.
Keywords: arf6; regulates gabaergic; arf6 regulates; small gtpase ... See more keywords