G2 and S phase‐expressed‐1 induces chromosomal instability in esophageal squamous cell carcinoma cells and inhibits cell apoptosis through ROS/JNK signaling
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23470
Abstract: New diagnostic and therapeutic strategies are urgently needed to improve the prognosis of patients with esophageal squamous cell carcinoma (ESCC), which has high morbidity and mortality. Bioinformatics analysis revealed that cell cycle regulation related molecular… read more here.
Keywords: cell; apoptosis; jnk signaling; gtse1 ... See more keywords
GTSE1 promotes prostate cancer cell proliferation via the SP1/FOXM1 signaling pathway
Sign Up to like & getrecommendations! Published in 2020 at "Laboratory Investigation"
DOI: 10.1038/s41374-020-00510-4
Abstract: G2 and S phase-expressed-1 (GTSE1) has been implicated in the pathogenesis of several malignant tumors. However, its specific role in prostate cancer (PCa) remains unclear. In this study, RNA-Seq data from patients with PCa and… read more here.
Keywords: foxm1; cell proliferation; prostate cancer; cancer ... See more keywords
GTSE1 promotes the growth of NSCLC by regulating microtubule-associated proteins through the ERK/MAPK pathway.
Sign Up to like & getrecommendations! Published in 2023 at "Thoracic cancer"
DOI: 10.1111/1759-7714.14908
Abstract: The role of G2 and S phase-expressed-1 (GTSE1), a microtubule-localized protein, in non-small-cell lung cancer (NSCLC) remains unknown. We explored its role in NSCLC growth. GTSE1 was detected in NSCLC tissues and cell lines using… read more here.
Keywords: growth; gtse1; microtubule associated; microtubule ... See more keywords
High GTSE1 expression promotes cell proliferation, metastasis and cisplatin resistance in ccRCC and is associated with immune infiltrates and poor prognosis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2023.996362
Abstract: Background: Clear cell renal cell carcinoma is the most common and fatal form of kidney cancer, accounting for 80% of new cases. Although it has been reported that GTSE1 is highly expressed in a variety… read more here.
Keywords: cell; prognosis; ccrcc; expression ... See more keywords