Gualou Guizhi Granule Protects Against Oxidative Injury by Activating Nrf2/ARE Pathway in Rats and PC12 Cells
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DOI: 10.1007/s11064-018-2507-x
Abstract: Stroke involves numerous pathophysiological processes and oxidative stress is considered as a main cellular event in its pathogenesis. The nuclear factor erythroid-2-related factor 2 (Nrf2)/antioxidant response element (ARE) pathway plays a key role in inducing… read more here.
Keywords: nrf2 pathway; oxidative injury; guizhi granule; gualou guizhi ... See more keywords
Gualou Guizhi decoction promotes therapeutic angiogenesis via the miR210/HIF/VEGF pathway in vivo and in vitro
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DOI: 10.1080/13880209.2023.2204142
Abstract: Abstract Context Gualou Guizhi decoction (GLGZD) is an ancient Chinese classical prescription widely used to treat ischemic stroke. However, the molecular mechanisms of GLGZD promoting angiogenesis are unavailable. Objective This study investigates the angiogenesis effect… read more here.
Keywords: gualou guizhi; hif; vivo vitro; hif vegf ... See more keywords