Combining Coarse-Grained Simulations and Single Molecule Analysis Reveals a Three-State Folding Model of the Guanidine-II Riboswitch
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DOI: 10.3389/fmolb.2022.826505
Abstract: Riboswitch RNAs regulate gene expression by conformational changes induced by environmental conditions and specific ligand binding. The guanidine-II riboswitch is proposed to bind the small molecule guanidinium and to subsequently form a kissing loop interaction… read more here.
Keywords: single molecule; guanidine riboswitch; grained simulations; riboswitch ... See more keywords