Guanosine, a guanine-based nucleoside relaxed isolated corpus cavernosum from mice through cGMP accumulation
Sign Up to like & getrecommendations! Published in 2020 at "Purinergic Signalling"
DOI: 10.1007/s11302-020-09702-5
Abstract: In corpus cavernosum (CC), guanosine triphosphate (GTP) is converted into cyclic guanosine monophosphate (cGMP) to induce erection. The action of cGMP is terminated by phosphodiesterases and efflux transporters, which pump cGMP out of the cell.… read more here.
Keywords: guanosine; corpus cavernosum; guanine based; cgmp ... See more keywords
Neuromodulatory Effects of Guanine-Based Purines in Health and Disease
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2018.00376
Abstract: The function of guanine-based purines (GBPs) is mostly attributed to the intracellular modulation of heteromeric and monomeric G proteins. However, extracellular effects of guanine derivatives have also been recognized. Thus, in the central nervous system… read more here.
Keywords: based purines; gbps; guanine based; neuromodulatory effects ... See more keywords