Recovery of the Formation and Function of Oxidized G-Quadruplexes by a Pyrene-Modified Guanine Tract.
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DOI: 10.1021/jacs.8b01577
Abstract: Oxidation is one of the frequent causes of DNA damage, especially to guanine bases. Guanine bases in the G-quadruplex (G4) are sensitive to damage by oxidation, resulting in transformation to 8-oxo-7,8-dihydroguanine (8-oxoG). Because the formation… read more here.
Keywords: pyrene modified; guanine tract; formation; formation function ... See more keywords