Systematically Modulating Aptamer Affinity and Specificity by Guanosine-to-Inosine Substitution.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c00422
Abstract: Aptamers are widely used in small molecule detection applications due to their specificity, stability, and cost effectiveness. One key challenge in utilizing aptamers in sensors is matching the binding affinity of the aptamer to the… read more here.
Keywords: affinity specificity; affinity; specificity guanosine; guanosine inosine ... See more keywords