Abstract 3128: Using Kmerizer, a germline and somatic genotyper for immune associated complex alleles in GuardantINFINITY, for immunotherapy response prediction using cfDNA
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DOI: 10.1158/1538-7445.am2023-3128
Abstract: Background: HLA germline genotypes and somatic mutations show great promise as emerging biomarkers for immune checkpoint inhibitors (ICIs) and understanding patient prognosis. Multiple studies have shown that HLA homozygosity or loss-of-function somatic mutations negatively correlates… read more here.
Keywords: response; kmerizer; prediction; guardantinfinity ... See more keywords