A lncRNA GUARDINg genome integrity
Sign Up to like & getrecommendations! Published in 2018 at "Nature Cell Biology"
DOI: 10.1038/s41556-018-0075-6
Abstract: A coordinated DNA damage response mediated by p53 to repair DNA lesions or to promote apoptosis is essential for maintenance of genome stability. A study now unveils the long non-coding RNA GUARDIN as a component… read more here.
Keywords: integrity; biology; genome integrity; guarding genome ... See more keywords
ATRX/DAXX: Guarding the Genome against the Hazards of ALT
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.3390/genes14040790
Abstract: Proliferating cells must enact a telomere maintenance mechanism to ensure genomic stability. In a subset of tumors, telomeres are maintained not by telomerase, but through a homologous recombination-based mechanism termed Alternative Lengthening of Telomeres or… read more here.
Keywords: daxx guarding; hazards alt; guarding genome; daxx ... See more keywords