GUCY2C maintains intestinal LGR5+ stem cells by opposing ER stress
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.22084
Abstract: Long-lived multipotent stem cells (ISCs) at the base of intestinal crypts adjust their phenotypes to accommodate normal maintenance and post-injury regeneration of the epithelium. Their long life, lineage plasticity, and proliferative potential underlie the necessity… read more here.
Keywords: gucy2c; stress; gucy2c mice; stem cells ... See more keywords