Micrometer scale guidance of mesenchymal stem cells to form structurally oriented large-scale tissue engineered cartilage.
Sign Up to like & getrecommendations! Published in 2017 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2017.07.016
Abstract: Current clinical methods to treat articular cartilage lesions provide temporary relief of the symptoms but fail to permanently restore the damaged tissue. Tissue engineering, using mesenchymal stem cells (MSCs) combined with scaffolds and bioactive factors,… read more here.
Keywords: tissue; guidance channels; mechanical properties; tissue engineered ... See more keywords
Optimization of nanofiber scaffold properties towards nerve guidance channel design
Sign Up to like & getrecommendations! Published in 2018 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.235023
Abstract: Nerve guidance channels are limited by lack of topographical guidance: Treatment of sizeable nerve gaps remains problematic following peripheral nerve injury. Functional outcomes are good when neurorrhaphy, or direct end-to-end suture repair, is possible. The… read more here.
Keywords: nanofiber scaffold; nerve guidance; guidance channels; generation ... See more keywords