Procalcitonin-guided antibiotic therapy algorithms for different types of acute respiratory infections based on previous trials
Sign Up to like & getrecommendations! Published in 2018 at "Expert Review of Anti-infective Therapy"
DOI: 10.1080/14787210.2018.1496331
Abstract: ABSTRACT Introduction: Although evidence indicates that use of procalcitonin to guide antibiotic decisions for the treatment of acute respiratory infections (ARI) decreases antibiotic consumption and improves clinical outcomes, algorithms used within studies had differences in… read more here.
Keywords: respiratory; procalcitonin guided; guided antibiotic; antibiotic therapy ... See more keywords
Impact of Pharmacist-Led Procalcitonin-Guided Antibiotic Therapy in Critically Ill Patients With Pneumonia
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DOI: 10.1177/0018578719836643
Abstract: Purpose: Procalcitonin (PCT) is a peptide that is released in response to bacterial infections. The 2016 Infectious Diseases Society of America pneumonia guidelines recommend PCT monitoring to help guide antibiotic discontinuation. Utilization of PCT is… read more here.
Keywords: group; antibiotic therapy; critically ill; guided antibiotic ... See more keywords
Do we need new trials of procalcitonin-guided antibiotic therapy?
Sign Up to like & getrecommendations! Published in 2018 at "Critical Care"
DOI: 10.1186/s13054-018-1948-6
Abstract: Using biomarkers as a guide to tailor the duration of antibiotic treatment in respiratory infections is an attractive hypothesis assessed in several studies. Recent work aiming to summarize the evidence assessed the effect of a… read more here.
Keywords: pct; duration; need new; evidence ... See more keywords
Procalcitonin-guided antibiotic therapy for pediatrics with infective disease: A updated meta-analyses and trial sequential analysis
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DOI: 10.3389/fcimb.2022.915463
Abstract: Objective We aimed to evaluate the effect of procalcitonin (PCT) guided therapy on antibiotic exposure in pediatric patients with infectious disease. Methods We performed an updated systematic review and meta-analysis of randomized controlled trials (RCTs)… read more here.
Keywords: antibiotic therapy; disease; therapy; pct guided ... See more keywords
γ-Core Guided Antibiotic Design Based on Human Enteric Defensin 5
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DOI: 10.3390/membranes13010051
Abstract: An increase in the number of infections caused by resistant bacteria worldwide necessitates the development of alternatives to antibiotics. Human defensin (HD) 5 is an innate immune peptide with broad-spectrum antibacterial activity, but its complicated… read more here.
Keywords: defensin; based human; antibiotic design; guided antibiotic ... See more keywords