Structure-guided combination therapy to potently improve the function of mutant CFTRs
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DOI: 10.1038/s41591-018-0200-x
Abstract: Available corrector drugs are unable to effectively rescue the folding defects of CFTR-ΔF508 (or CFTR-F508del), the most common disease-causing mutation of the cystic fibrosis transmembrane conductance regulator, a plasma membrane (PM) anion channel, and thus… read more here.
Keywords: therapy; structure guided; guided combination; function ... See more keywords
Ultrasonography-Guided Combination with Elbow Arthrography-Assisted Minimally Invasive Treatment of Radial Neck Fractures in Young Children
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DOI: 10.1155/2022/6840716
Abstract: Background A radius neck fracture in children is a common fracture that not only affects the growth and development of children but also has a certain impact on the function of children's elbow joints. Objective… read more here.
Keywords: neck fractures; neck; guided combination; group ... See more keywords