Computational guided drug repurposing for targeting 2′-O-ribose methyltransferase of SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2020 at "Life Sciences"
DOI: 10.1016/j.lfs.2020.118169
Abstract: Abstract Aims The recent outbreak of pandemic severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has led the world towards a global health emergency. Currently, no proper medicine or effective treatment strategies are available; therefore, repurposing of… read more here.
Keywords: omtase; analysis; drug repurposing; guided drug ... See more keywords
Ultrasound-guided drug delivery in cancer
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DOI: 10.14366/usg.17021
Abstract: Recent advancements in ultrasound and microbubble (USMB) mediated drug delivery technology has shown that this approach can improve spatially confined delivery of drugs and genes to target tissues while reducing systemic dose and toxicity. The… read more here.
Keywords: drug delivery; delivery; ultrasound guided; guided drug ... See more keywords
The outcomes of intravascular ultrasound-guided drug-eluting stent implantation among patients with complex coronary lesions: a comprehensive meta-analysis of 15 clinical trials and 8,084 patients
Sign Up to like & getrecommendations! Published in 2017 at "Anatolian Journal of Cardiology"
DOI: 10.14744/anatoljcardiol.2016.7461
Abstract: OBJECTIVE The effects of intravascular ultrasound (IVUS)-guided drug-eluting stent (DES) implantation in patients with complex coronary artery lesions remains to be controversial. This study sought to evaluate the outcomes of IVUS guidance in these patients.… read more here.
Keywords: drug eluting; intravascular ultrasound; patients complex; guided drug ... See more keywords
In silico Guided Drug Repurposing: Discovery of New Competitive and Non-competitive Inhibitors of Falcipain-2
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2019.00534
Abstract: Malaria is among the leading causes of death worldwide. The emergence of Plasmodium falciparum resistant strains with reduced sensitivity to the first line combination therapy and suboptimal responses to insecticides used for Anopheles vector management… read more here.
Keywords: drug repurposing; non competitive; guided drug; repurposing discovery ... See more keywords
Nanoengineered, magnetically guided drug delivery for tumors: A developmental study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2022.1013994
Abstract: Fighting against tumors is an ongoing challenge in both medicinal and clinical applications. In recent years, chemotherapy, along with surgery, has significantly improved the situation to prolong life expectancy. Theoretically, and regardless of dosage, we… read more here.
Keywords: guided drug; nanoengineered magnetically; magnetically guided; drug delivery ... See more keywords
Externalization of Mitochondrial PDCE2 on Irradiated Endothelium as a Target for Radiation-Guided Drug Delivery and Precision Thrombosis of Pathological Vasculature
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23168908
Abstract: Endothelial cells are highly sensitive to ionizing radiation, and exposure leads to multiple adaptive changes. Remarkably, part of this response is the translocation of normally intracellular proteins to the cell surface. It is unclear whether… read more here.
Keywords: guided drug; precision thrombosis; drug delivery; radiation ... See more keywords