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Published in 2018 at "Movement Disorders"
DOI: 10.1002/mds.27401
Abstract: Background: Magnetic resonance imaging–guided focused ultrasound thalamotomy is approved by the U.S. Food and Drug Administration for treatment of essential tremor. Although this incisionless technology creates an ablative lesion, it potentially avoids serious complications of… read more here.
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Published in 2022 at "Movement Disorders"
DOI: 10.1002/mds.28918
Abstract: Spinocerebellar ataxias (SCAs) are progressive, neurodegenerative disorders generally associated with a variety of symptoms. The SCA12 is typically associated with action tremor of the upper extremity, and symptomatic treatment is challenging. Stereotactic neurosurgery is performed… read more here.
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Published in 2022 at "Movement Disorders"
DOI: 10.1002/mds.29190
Abstract: GBA1 mutation is the most common genetic risk factor for Parkinson's disease (PD). Replacement of the lysosomal enzyme glucocerebrosidase (GCase) slows neurodegeneration in PD models and may be a promising disease‐modifying therapy in patients with… read more here.
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Published in 2025 at "Movement Disorders"
DOI: 10.1002/mds.30188
Abstract: Magnetic resonance‐guided focused ultrasound (MRgFUS) is an established surgical treatment for essential tremor, providing tremor relief without the need for an incision or general anesthesia. Meta‐analyses have been limited in their exploration of the durability… read more here.
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Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9139-6_10
Abstract: Recombinant adeno-associated viral (rAAV) vectors are a promising tool for therapeutic gene delivery to the brain. However, the delivery of rAAVs across the blood-brain barrier (BBB) and entry into the brain remains a major challenge… read more here.
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Published in 2020 at "European Radiology"
DOI: 10.1007/s00330-020-06712-0
Abstract: To assess the intraoperative neuroimaging findings in patients treated with transcranial MR-guided focused ultrasound (tcMRgFUS) thalamotomy using 1.5T equipment in comparison with the 48-h follow-up. Fifty prospectively enrolled patients undergoing unilateral tcMRgFUS thalamotomy for either… read more here.
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Published in 2020 at "European Radiology"
DOI: 10.1007/s00330-020-07076-1
Abstract: Objective To develop and evaluate a T 2 MR–based radiomics prediction model incorporating radiomics features and clinical parameters to predict the response to magnetic resonance–guided focused ultrasound surgery (MRgFUS) in patients with adenomyosis. Materials and… read more here.
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Published in 2021 at "Neurological Sciences"
DOI: 10.1007/s10072-021-05443-4
Abstract: To evaluate the safety and efficacy of magnetic resonance-guided focused ultrasound (MRgFUS) in the treatment of Parkinson’s disease (PD). The databases of Medline, EMBASE, and the Cochrane Library were searched for eligible randomized controlled trials… read more here.
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Published in 2020 at "Academic radiology"
DOI: 10.1016/j.acra.2020.06.013
Abstract: OBJECTIVES The aim of this study was to evaluate the impact of technology improvements on the outcomes of magnetic resonance-guided focused ultrasound (MRgFUS) treatments of symptomatic uterine leiomyomas (uterine fibroids). The study compared ablation volumes… read more here.
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Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-85811-8
Abstract: Parkinson’s disease (PD) is a progressive disorder that affects the nervous system and causes regions of the brain to deteriorate. In this study, we investigated the effects of MR-guided focused ultrasound (MRgFUS) for the delivery… read more here.
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Published in 2021 at "Seminars in musculoskeletal radiology"
DOI: 10.1055/s-0041-1735472
Abstract: Magnetic resonance-guided focused ultrasound (MRgFUS) is a novel noninvasive therapy that uses focused sound energy to thermally ablate focal pathology within the body. In the United States, MRgFUS is approved by the Food and Drug… read more here.