Bioassay-guided fractionation and identification of wound healing active compound from Pistacia vera L. hull extract.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2019.112335
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Pistachio hull has traditionally been used to treat peptic ulcer, hemorrhoids, oral and cutaneous wounds. AIM OF THE STUDY On the basis of its traditional uses and previous pharmacological reports, a bioassay guided… read more here.
Keywords: wound healing; active compound; guided fractionation; vera ... See more keywords
Acetylcholinesterase‐inhibitory activity of Iranian plants: Combined HPLC/bioassay‐guided fractionation, molecular networking and docking strategies for the dereplication of active compounds
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2018.06.026
Abstract: HIGHLIGHTSPrangos ferulacea was the most active plant against the acetylcholinesterase enzyme.Metabolites were analyzed by bioassay‐guided fractionation and molecular networking.Phytochemical analysis of the active extract led to the identification of 17 compounds.Flavonoids showed a high affinity… read more here.
Keywords: guided fractionation; bioassay guided; fractionation molecular; molecular networking ... See more keywords
Determination of Phenolics and Flavonoids of Some Useful Medicinal Plants and Bioassay-Guided Fractionation Substances of Sclerocarya birrea (A. Rich) Hochst Stem (Bark) Extract and Their Efficacy Against Salmonella typhi
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2021.670530
Abstract: Gallic acid and catechin are the most abundant phenolic and flavonoid contents found in all plant extracts. The contents and the bioassay-guided fractionating substances of the Sclerocarya birrea (A. Rich) Hochst (Anacardiaceae) fraction played vital… read more here.
Keywords: guided fractionation; bioassay guided; stem bark; stem ... See more keywords
Bio-Guided Fractionation of Ethanol Extract of Leaves of Esenbeckia alata Kunt (Rutaceae) Led to the Isolation of Two Cytotoxic Quinoline Alkaloids: Evidence of Selectivity Against Leukemia Cells
Sign Up to like & getrecommendations! Published in 2019 at "Biomolecules"
DOI: 10.3390/biom9100585
Abstract: Bio-guided fractionation performed on the leaves-derived ethanol extract of Esenbeckia alata (Rutaceae), a plant used in traditional medicine, led to the isolation of two alkaloids, kokusaginine 1 and flindersiamine 2, as main cytotoxic agents. Primary… read more here.
Keywords: guided fractionation; esenbeckia alata; ethanol extract; bio guided ... See more keywords
Bioassay-Guided Fractionation Leads to the Detection of Cholic Acid Generated by the Rare Thalassomonas sp.
Sign Up to like & getrecommendations! Published in 2022 at "Marine Drugs"
DOI: 10.3390/md21010002
Abstract: Bacterial symbionts of marine invertebrates are rich sources of novel, pharmaceutically relevant natural products that could become leads in combatting multidrug-resistant pathogens and treating disease. In this study, the bioactive potential of the marine invertebrate… read more here.
Keywords: fractionation leads; guided fractionation; leads detection; cholic acid ... See more keywords
Bioassay-Guided Fractionation of Siparuna glycycarpa n-Butanol Extract with Inhibitory Activity against Influenza A(H1N1)pdm09 Virus by Centrifugal Partition Chromatography (CPC)
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27020399
Abstract: Siparuna glycycarpa occurs in the Amazon region, and some species of this genus are used in Brazilian folk medicine. A recent study showed the inhibitory effect of this species against influenza A(H1N1)pdm09 virus, and in… read more here.
Keywords: pdm09 virus; guided fractionation; h1n1 pdm09; bioassay guided ... See more keywords
Bioassay-Guided Fractionation with Antimalarial and Antimicrobial Activities of Paeonia officinalis
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27238382
Abstract: Bioassay-guided fractionation technique of roots of Paeonia officinalis led to isolation and structure elucidation of seven known compounds, including four monoterpene glycosides: lactiflorin (1), paeoniflorin (4), galloyl paeoniflorin (5), and (Z)-(1S,5R)-β-pinen-10-yl β-vicianoside (7); two phenolics:… read more here.
Keywords: guided fractionation; ic50; paeonia officinalis; bioassay guided ... See more keywords
Antioxidant Guided Fractionation of Blackberry Polyphenols Show Synergistic Role of Catechins and Ellagitannins
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28041933
Abstract: In the present study, blackberry extract was prepared using a previously optimized solid–liquid extraction method in 70% aqueous acetone aimed at the recovery of its principal phenolics. Subsequently, 0.5 g of freeze-dried extract was subjected… read more here.
Keywords: role; guided fractionation; antioxidant guided; fractionation ... See more keywords
Bioassay Guided Fractionation Protocol for Determining Novel Active Compounds in Selected Australian Flora
Sign Up to like & getrecommendations! Published in 2022 at "Plants"
DOI: 10.3390/plants11212886
Abstract: A large variety of unique and distinct flora of Australia have developed exceptional survival methods and phytochemicals and hence may provide a significant avenue for new drug discovery. This study proposes a bioassay guided fractionation… read more here.
Keywords: ggl; guided fractionation; fractionation; acid ... See more keywords
Bio-Guided Fractionation Driven by In Vitro α-Amylase Inhibition Assays of Essential Oils Bearing Specialized Metabolites with Potential Hypoglycemic Activity
Sign Up to like & getrecommendations! Published in 2020 at "Plants"
DOI: 10.3390/plants9091242
Abstract: Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by unpaired blood glycaemia maintenance. T2DM can be treated by inhibiting carbohydrate hydrolyzing enzymes (α-amylases and α-glucosidases) to decrease postprandial hyperglycemia. Acarbose and voglibose are… read more here.
Keywords: specialized metabolites; guided fractionation; amylase; bio guided ... See more keywords