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   Articles with "guided isolation" as a keyword



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Bioassay-guided isolation and evaluation of anti-osteoporosis active polysaccharides from Morinda officinalis.

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recommendations! Published in 2020 at "Journal of ethnopharmacology"

DOI: 10.1016/j.jep.2020.113113

Abstract: ETHNOPHARMACOLOGICAL RELEVANCE As a famous Chinese tonic herb for the bones and joints, the clinical efficacy of Morinda officinalis has shown its advantages in the treatment of bone disease. However, the anti-osteoporosis potential and responsible… read more here.

Keywords: anti osteoporosis; bioassay guided; morinda officinalis; guided isolation ... See more keywords
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Bioassay-guided isolation of antiplasmodial and antimicrobial constituents from the roots of Terminalia albida.

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recommendations! Published in 2020 at "Journal of ethnopharmacology"

DOI: 10.1016/j.jep.2020.113624

Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Terminalia albida (Combretaceae), widely used in Guinean traditional medicine, showed promising activity against Plasmodium falciparum and Candida albicans in previous studies. Bioassay-guided fractionation was carried out in order to isolate the compounds responsible… read more here.

Keywords: bioassay guided; guided isolation; terminalia albida; isolation antiplasmodial ... See more keywords
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Bioassay-guided isolation of urease inhibitors from Ferula narthex Bioss

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recommendations! Published in 2019 at "South African Journal of Botany"

DOI: 10.1016/j.sajb.2018.07.011

Abstract: Abstract The current study was designed to evaluate the urease inhibitory activities of the fractions of Ferula narthex Bioss, followed by bioassay guided isolation of new urease sesquiterpene coumarins, as potential urease inhibitors. The chloroform… read more here.

Keywords: urease inhibitors; ferula narthex; bioassay guided; narthex bioss ... See more keywords
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UPLC-MSE Guided Isolation of New Antifeedant Limonoids from Fruits of Trichilia connaroides.

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recommendations! Published in 2020 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.0c00862

Abstract: UPLC-MSE guided isolation of CHCl3 extract from the fruits of Trichilia connaroides yielded two new mexicanolide-type limonoids trichanolide F (1) and trichanolide G (2) along with a known compound carapanolide U (3). The structures of… read more here.

Keywords: trichilia connaroides; uplc mse; fruits trichilia; guided isolation ... See more keywords
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Bioassay-Guided Isolation of Antibacterial Metabolites from Emericella sp. TJ29.

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recommendations! Published in 2017 at "Journal of natural products"

DOI: 10.1021/acs.jnatprod.7b00077

Abstract: Bioassay-guided isolation of metabolites from cultures of the plant-derived fungus Emericella sp. TJ29 yielded three new terpene-polyketide hybrid meroterpenoids, emervaridones A-C (1-3), two new polyketides, varioxiranediols A and B (5 and 6), and three known… read more here.

Keywords: bioassay guided; isolation antibacterial; guided isolation; emericella tj29 ... See more keywords
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N-Methylneolitsine as a new and potent acetylcholinesterase inhibitor of Cissampelos pareira Linn. aerial parts: bioassay-guided isolation and quantitative densitometric analysis.

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recommendations! Published in 2023 at "Natural product research"

DOI: 10.1080/14786419.2023.2209819

Abstract: The rising geriatric population is expected to increase the demand for drugs treating neurodegenerative diseases. The present work is aimed to discover acetylcholinesterase (AChE) inhibitors from Cissampelos pareira Linn. aerial parts (Family: Menispermaceae). Bioassay-guided isolation,… read more here.

Keywords: guided isolation; pareira linn; linn aerial; cissampelos pareira ... See more keywords
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Bioassay-Guided Isolation of Antiplasmodial Compounds from Hypericum lanceolatum Lam. (Hypericaceae) and Their Cytotoxicity and Molecular Docking

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recommendations! Published in 2023 at "BioMed Research International"

DOI: 10.1155/2023/4693765

Abstract: In Cameroon, malaria is still the cause of several deaths yearly and leading to the continued search for new potent leads to fight against Plasmodium falciparum. Medicinal plants like Hypericum lanceolatum Lam. are introduced in… read more here.

Keywords: molecular docking; hypericum lanceolatum; guided isolation; bioassay guided ... See more keywords
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TLC Bioautography-guided Isolation and Antimicrobial, Antifungal Effects of 12 Alkaloids from Hylomecon japonica Roots§

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recommendations! Published in 2017 at "Natural Product Communications"

DOI: 10.1177/1934578x1701200914

Abstract: Hylomecon japonica (Thunb.) Prantl. is a Chinese medicinal plant whose active components and their antimicrobial mechanism was studied by TLC bioautography-guided isolation and identification of 12 alkaloids and their antimicrobial activities evaluated using the standard… read more here.

Keywords: guided isolation; bioautography guided; tlc bioautography; hylomecon japonica ... See more keywords
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Bioassay-guided isolation of Fenghuang Dancong tea constituents with α-glucosidase inhibition activities

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recommendations! Published in 2022 at "Frontiers in Nutrition"

DOI: 10.3389/fnut.2022.1050614

Abstract: An α-glucosidase inhibition assay showed the ethanolic extract of Fenghuang Dancong tea had potential α-glucosidase inhibitory activity. The most bioactive fraction, which was obtained via bioassay-guided isolation of the extract, was further purified to create… read more here.

Keywords: guided isolation; glucosidase inhibition; bioassay guided; fenghuang dancong ... See more keywords
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Bio-Guided Isolation of Compounds from Fraxinus excelsior Leaves with Anti-Inflammatory Activity

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recommendations! Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24043750

Abstract: Inflammation is the first physiological defence mechanism against external and internal stimuli. The prolonged or inappropriate response of the immune system may lead to the persistent inflammatory response that can potentially become a basis for… read more here.

Keywords: guided isolation; bio guided; anti inflammatory; receptor expression ... See more keywords
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Bioassay-Guided Isolation of Triterpenoids as α-Glucosidase Inhibitors from Cirsium setosum

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recommendations! Published in 2019 at "Molecules"

DOI: 10.3390/molecules24101844

Abstract: Cirsium setosum (C. setosum) has a potential antihyperglycemic effect, but it is unclear what bioactive components play a key role. According to the α-glucosidase inhibition activity, three new taraxastane-type triterpenoids of 3β-hydroxy-30-hydroperoxy-20-taraxastene (1), 3β-hydroxy-22α-methoxy-20-taraxastene (2),… read more here.

Keywords: isolation triterpenoids; bioassay guided; triterpenoids glucosidase; guided isolation ... See more keywords