Bioassay-guided isolation and evaluation of anti-osteoporosis active polysaccharides from Morinda officinalis.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2020.113113
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE As a famous Chinese tonic herb for the bones and joints, the clinical efficacy of Morinda officinalis has shown its advantages in the treatment of bone disease. However, the anti-osteoporosis potential and responsible… read more here.
Keywords: anti osteoporosis; bioassay guided; morinda officinalis; guided isolation ... See more keywords
Bioassay-guided isolation of antiplasmodial and antimicrobial constituents from the roots of Terminalia albida.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2020.113624
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Terminalia albida (Combretaceae), widely used in Guinean traditional medicine, showed promising activity against Plasmodium falciparum and Candida albicans in previous studies. Bioassay-guided fractionation was carried out in order to isolate the compounds responsible… read more here.
Keywords: bioassay guided; guided isolation; terminalia albida; isolation antiplasmodial ... See more keywords
Bioassay-guided isolation of urease inhibitors from Ferula narthex Bioss
Sign Up to like & getrecommendations! Published in 2019 at "South African Journal of Botany"
DOI: 10.1016/j.sajb.2018.07.011
Abstract: Abstract The current study was designed to evaluate the urease inhibitory activities of the fractions of Ferula narthex Bioss, followed by bioassay guided isolation of new urease sesquiterpene coumarins, as potential urease inhibitors. The chloroform… read more here.
Keywords: urease inhibitors; ferula narthex; bioassay guided; narthex bioss ... See more keywords
UPLC-MSE Guided Isolation of New Antifeedant Limonoids from Fruits of Trichilia connaroides.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.0c00862
Abstract: UPLC-MSE guided isolation of CHCl3 extract from the fruits of Trichilia connaroides yielded two new mexicanolide-type limonoids trichanolide F (1) and trichanolide G (2) along with a known compound carapanolide U (3). The structures of… read more here.
Keywords: trichilia connaroides; uplc mse; fruits trichilia; guided isolation ... See more keywords
Bioassay-Guided Isolation of Antibacterial Metabolites from Emericella sp. TJ29.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.7b00077
Abstract: Bioassay-guided isolation of metabolites from cultures of the plant-derived fungus Emericella sp. TJ29 yielded three new terpene-polyketide hybrid meroterpenoids, emervaridones A-C (1-3), two new polyketides, varioxiranediols A and B (5 and 6), and three known… read more here.
Keywords: bioassay guided; isolation antibacterial; guided isolation; emericella tj29 ... See more keywords
Bioassay-Guided Isolation and Identification of Cytotoxic Compounds from Melaleuca quinquenervia Fruits
Sign Up to like & getrecommendations! Published in 2024 at "ACS Omega"
DOI: 10.1021/acsomega.4c00769
Abstract: The fruit extract of Melaleuca quinquenervia yielded a total of 19 compounds, including two novel spiro-biflavonoid enantiomers (1a and 1b) and a chalcone derivative (3). Their structures were determined through spectroscopic analysis. The enantiomers of… read more here.
Keywords: isolation identification; melaleuca quinquenervia; guided isolation; quinquenervia ... See more keywords
LC-HRMS/MS-Guided Isolation of Unusual Diarylheptanoids from the Rhizomes of Alpinia officinarum
Sign Up to like & getrecommendations! Published in 2024 at "ACS Omega"
DOI: 10.1021/acsomega.4c07987
Abstract: LC-HRMS/MS analysis facilitated the precise targeting, isolation, and identification of unusual dimeric diarylheptanoids from Alpinia officinarum (A. officinarum). The tandem MS data for (4E)-1,7-diphenyl-4-hepten-3-one (7) revealed fragment ions at m/z 91, 105, and 117, which… read more here.
Keywords: hrms guided; unusual diarylheptanoids; isolation unusual; guided isolation ... See more keywords
Bioassay-guided isolation of terpenoids from the soft coral Sclerophytum humesi and assessment of their antidiabetic and cytotoxic activities
Sign Up to like & getrecommendations! Published in 2025 at "RSC Advances"
DOI: 10.1039/d5ra04971g
Abstract: This study represents the first report on the secondary metabolites from the soft coral Sclerophytum humesi. Nine terpenoids (1–9) were isolated by antidiabetic-guided isolation, including a new xeniaphyllane-type diterpenoid (Sclerohumin O, 1) and a new… read more here.
Keywords: sclerophytum humesi; coral sclerophytum; sclerophytum; guided isolation ... See more keywords
N-Methylneolitsine as a new and potent acetylcholinesterase inhibitor of Cissampelos pareira Linn. aerial parts: bioassay-guided isolation and quantitative densitometric analysis.
Sign Up to like & getrecommendations! Published in 2023 at "Natural product research"
DOI: 10.1080/14786419.2023.2209819
Abstract: The rising geriatric population is expected to increase the demand for drugs treating neurodegenerative diseases. The present work is aimed to discover acetylcholinesterase (AChE) inhibitors from Cissampelos pareira Linn. aerial parts (Family: Menispermaceae). Bioassay-guided isolation,… read more here.
Keywords: guided isolation; pareira linn; linn aerial; cissampelos pareira ... See more keywords
Bioassay-guided isolation of cycloartane-type triterpenes, their cytotoxic properties and identification of potential chemical markers from Geniotrigona thoracica propolis
Sign Up to like & getrecommendations! Published in 2024 at "Natural Product Research"
DOI: 10.1080/14786419.2024.2352867
Abstract: Abstract Phytochemical investigation through cytotoxicity bioassay-guided isolation of Geniotrigona thoracica propolis led to the identification of five cycloartane-type triterpenes, including mangiferonic acid 1, ambonic acid 2, mangiferolic acid 3, ambolic acid 4 and cycloartenol 5.… read more here.
Keywords: geniotrigona thoracica; cycloartane type; guided isolation; isolation ... See more keywords
Bioassay-Guided Isolation of Antiplasmodial Compounds from Hypericum lanceolatum Lam. (Hypericaceae) and Their Cytotoxicity and Molecular Docking
Sign Up to like & getrecommendations! Published in 2023 at "BioMed Research International"
DOI: 10.1155/2023/4693765
Abstract: In Cameroon, malaria is still the cause of several deaths yearly and leading to the continued search for new potent leads to fight against Plasmodium falciparum. Medicinal plants like Hypericum lanceolatum Lam. are introduced in… read more here.
Keywords: molecular docking; hypericum lanceolatum; guided isolation; bioassay guided ... See more keywords