Peptide-guided lipid nanoparticles deliver mRNA to the neural retina of rodents and nonhuman primates
Sign Up to like & getrecommendations! Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.add4623
Abstract: Lipid nanoparticle (LNP)–based mRNA delivery holds promise for the treatment of inherited retinal degenerations. Currently, LNP-mediated mRNA delivery is restricted to the retinal pigment epithelium (RPE) and Müller glia. LNPs must overcome ocular barriers to… read more here.
Keywords: ller glia; mrna delivery; retina; peptide guided ... See more keywords