Articles with "guided mutagenesis" as a keyword



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Structure‐guided Mutagenesis Reveals the Catalytic Residue that Controls the Regiospecificity of C6‐Indole Prenyltransferases

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Published in 2023 at "ChemCatChem"

DOI: 10.1002/cctc.202300423

Abstract: Indole is a significant structural moiety and functionalization of the C−H bond in indole‐containing molecules expands their chemical space, and modifies their properties and/or activities. Indole prenyltransferases (IPTs) catalyze the direct regiospecific installation of prenyl… read more here.

Keywords: structure guided; guided mutagenesis; indole prenyltransferases; regiospecificity ... See more keywords