Structure‐guided stabilization of pathogen‐derived peptide‐HLA‐E complexes using non‐natural amino acids conserves native TCR recognition
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DOI: 10.1002/eji.202149745
Abstract: The nonpolymorphic class Ib molecule, HLA‐E, primarily presents peptides from HLA class Ia leader peptides, providing an inhibitory signal to NK cells via CD94/NKG2 interactions. read more here.
Keywords: derived peptide; stabilization pathogen; peptide hla; pathogen derived ... See more keywords