Organic NIR‐II Nanofluorophore with Ultrahigh Quantum Yield for Vessels Imaging and Fluorescence Image‐Guided Surgery
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202413341
Abstract: The second near‐infrared window (NIR‐II) fluorescence imaging has aroused more and more interest in biomedical applications due to negligible autofluorescence and deep penetration ability. However, the fluorescence quantum yield of NIR‐II fluorophores with more than… read more here.
Keywords: guided surgery; fluorescence; ctb1125; quantum yield ... See more keywords
Novel fluorescent GLUT1 inhibitor for precision detection and fluorescence image‐guided surgery in oral squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34049
Abstract: Early detection and complete resection of oral squamous cell carcinoma (OSCC) are crucial to improving patient survival and prognosis. However, specifically targeted imaging probes for OSCC detection are limited. Our study aimed to synthesize a… read more here.
Keywords: fluorescence image; detection; fluorescence; image guided ... See more keywords
A novel in vivo Cerenkov luminescence image-guided surgery on primary and metastatic colorectal cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of biophotonics"
DOI: 10.1002/jbio.201960152
Abstract: Intraoperative Cerenkov luminescence imaging (CLI) can effectively improve the performance of tumor surgery. Nevertheless, the existing approaches are still unsatisfying to the clinical demands of open surgery. This study develops a novel intraoperative in vivo… read more here.
Keywords: cerenkov luminescence; guided surgery; image guided;
Fluorescent‐guided surgery for sentinel lymph node detection in gastric cancer and carcinoembryonic antigen targeted fluorescent‐guided surgery in colorectal and pancreatic cancer
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.25139
Abstract: Sentinel lymph node procedures for gastric cancer resections using indocyanine green (ICG) linked to Nanocoll outperformed normal ICG but did not provide information on possible lymph node metastasis. Carcinoembryonic antigen targeted fluorescent imaging using SGM‐101… read more here.
Keywords: cancer; lymph node; guided surgery; fluorescent guided ... See more keywords
State of the art medical devices for fluorescence-guided surgery (FGS): technical review and future developments
Sign Up to like & getrecommendations! Published in 2024 at "Surgical Endoscopy"
DOI: 10.1007/s00464-024-11236-5
Abstract: Medical devices for fluorescence-guided surgery (FGS) are becoming available at a fast pace. The main challenge for surgeons lies in the lack of in-depth knowledge of optical imaging, different technical specifications and poor standardisation, and… read more here.
Keywords: surgery; devices fluorescence; fluorescence; guided surgery ... See more keywords
Nanoparticle Formulation of Indocyanine Green Improves Image-Guided Surgery in a Murine Model of Breast Cancer
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Imaging and Biology"
DOI: 10.1007/s11307-019-01462-y
Abstract: Purpose Negative surgical margins (NSMs) have favorable prognostic implications in breast tumor resection surgery. Fluorescence image-guided surgery (FIGS) has the ability to delineate surgical margins in real time, potentially improving the completeness of tumor resection.… read more here.
Keywords: indocyanine green; breast; breast cancer; guided surgery ... See more keywords
Image-guided surgery of head and neck carcinoma in rabbit models by intra-operatively defining tumour-infiltrated margins and metastatic lymph nodes
Sign Up to like & getrecommendations! Published in 2019 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2019.10.055
Abstract: Background The infiltrative nature and lymphatic metastasis of head and neck squamous cell carcinoma (HNSCC) are the main reasons leading to its poor prognosis. Methods A multimodal surface-enhanced resonance Raman spectroscopy (SERRS) and magnetic resonance… read more here.
Keywords: lymph nodes; guided surgery; metastatic lymph; head neck ... See more keywords
SGM-101: An innovative near-infrared dye-antibody conjugate that targets CEA for fluorescence-guided surgery.
Sign Up to like & getrecommendations! Published in 2017 at "Surgical oncology"
DOI: 10.1016/j.suronc.2017.03.002
Abstract: PURPOSE Fluorescence-guided surgery (FGS) provides surgeons with new opportunities to improve real-time cancer nodule detection and tumor margin visualization. Currently, the most important challenge in this field is the development of fluorescent dyes that specifically… read more here.
Keywords: sgm 101; antibody; fluorescence guided; guided surgery ... See more keywords
Preclinical Evaluation of a Humanized, Near-Infrared Fluorescent Antibody for Fluorescence-Guided Surgery of MUC16-Expressing Pancreatic Cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00203
Abstract: Surgery remains the only potentially curative treatment option for pancreatic cancer, but resections are made more difficult by infiltrative disease, proximity of critical vasculature, peritumoral inflammation, and dense stroma. Surgeons are limited to tactile and… read more here.
Keywords: pancreatic cancer; fluorescence guided; cancer; guided surgery ... See more keywords
High-Contrast Detection of Somatostatin Receptor Subtype-2 for Fluorescence-Guided Surgery
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00583
Abstract: Dye design can influence the ability of fluorescently labeled imaging agents to generate tumor contrast and has become an area of significant interest in the field of fluorescence-guided surgery (FGS). Here, we show that the… read more here.
Keywords: contrast; fnir tag; fluorescence guided; somatostatin receptor ... See more keywords
In Vivo Evaluation of a Gallium-68-Labeled Tumor-Tracking Cyanine Dye for Positron Emission Tomography/Near-Infrared Fluorescence Carcinoma Imaging, Image-Guided Surgery, and Photothermal Therapy
Sign Up to like & getrecommendations! Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.2c08235
Abstract: Positron emission tomography (PET)/near-infrared fluorescence (NIRF) dual-modal imaging presents an enticing prospect for tumor diagnosis and surgical navigation. In this study, we developed a novel probe IR808-DOTA for tumor-targeted PET/NIRF imaging, image-guided surgery, and photothermal… read more here.
Keywords: positron emission; ir808; surgery; emission tomography ... See more keywords