Articles with "guinea pig" as a keyword



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Maternal separation increases later immobility during forced swim in guinea pig pups: evidence for sensitization of a depressive‐like state

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Published in 2017 at "Developmental Psychobiology"

DOI: 10.1002/dev.21444

Abstract: Early-life stress is thought to increase later vulnerability for developing depressive illness by sensitizing underlying stress-responsive systems. Guinea pig pups separated from their mother and isolated in a novel cage for 3 hr exhibit a sensitized… read more here.

Keywords: guinea; guinea pig; pig pups; separation ... See more keywords
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Fluoride or/and aluminum induced toxicity in guinea pig teeth with the low expression of dentine phosphoprotein

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Published in 2017 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.21912

Abstract: This study investigated the damage and expression of dentine phosphoprotein (DPP) in guinea pig teeth by the administration of fluoride (F) or/and aluminum (Al). Fifty‐two guinea pigs were divided randomly into four groups (control, F,… read more here.

Keywords: guinea pig; dentine phosphoprotein; expression dentine; expression ... See more keywords
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The Generation of a Comprehensive Spectral Library for the Analysis of the Guinea Pig Proteome by SWATH‐MS

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Published in 2019 at "Proteomics"

DOI: 10.1002/pmic.201900156

Abstract: Advances in liquid chromatography‐mass spectrometry have facilitated the incorporation of proteomic studies to many biology experimental workflows. Data‐independent acquisition platforms, such as sequential window acquisition of all theoretical mass spectra (SWATH‐MS), offer several advantages for… read more here.

Keywords: guinea; guinea pig; comprehensive spectral; swath ... See more keywords
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CT anatomy of the lungs, bronchi and trachea in the Mature Guinea pig (cavia porcellus)

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Published in 2023 at "Veterinary Medicine and Science"

DOI: 10.1002/vms3.1131

Abstract: Abstract Background Since there is no complete study of topographic features of thorax structures in guinea pigs, this study strives to define the exact topographic features of thorax structures. Objectives The aim of this study… read more here.

Keywords: cavity; guinea pigs; guinea; anatomy ... See more keywords
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Electrophysiologic Studies on the Risks and Potential Mechanism Underlying the Proarrhythmic Nature of Azithromycin

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Published in 2017 at "Cardiovascular Toxicology"

DOI: 10.1007/s12012-017-9401-7

Abstract: Abstract The mechanisms underlying arrhythmia induced by the clinical use of azithromycin are poorly understood. We aimed to investigate the proarrhythmic effects of azithromycin using electrocardiogram (ECG) and ion channel models. In vivo and in… read more here.

Keywords: guinea pig; times crc; electrophysiologic studies; potential mechanism ... See more keywords
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Mechanisms of electrical remodeling in lipotoxic guinea pig heart.

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Published in 2019 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2019.09.051

Abstract: OBJECTIVES To develop an adult guinea pig model of lipotoxicity and explore the underlying mechanisms associated with changes in the expression of the delayed rectifier potassium current (IK). BACKGROUND Lipotoxicity may represent a common link… read more here.

Keywords: guinea; guinea pig; lipotoxic guinea; remodeling lipotoxic ... See more keywords
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Mechanisms for pituitary adenylate cyclase-activating polypeptide-induced increase in excitability in guinea-pig and mouse adrenal medullary cells.

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Published in 2020 at "European journal of pharmacology"

DOI: 10.1016/j.ejphar.2020.172956

Abstract: Pituitary adenylate cyclase-activating polypeptide (PACAP) acts on adrenal medullary (AM) cells as a neurotransmitter of the sympathetic preganglionic nerve. In guinea-pig AM cells, PACAP induces little catecholamine secretion, but enhances secretion evoked by stimulants, whereas… read more here.

Keywords: guinea; guinea pig; pituitary adenylate; adenylate cyclase ... See more keywords
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Unusual mechanical processing of sounds at the apex of the Guinea pig cochlea

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Published in 2018 at "Hearing Research"

DOI: 10.1016/j.heares.2018.09.009

Abstract: ABSTRACT One of the tenets of mammalian auditory physiology is that the frequency selectivity at the cochlear base decreases as a function of stimulus level. Changes in frequency selectivity have been shown to be accompanied… read more here.

Keywords: guinea pig; frequency selectivity; cochlea; pig cochlea ... See more keywords
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Simultaneous rather than retrograde spiral ganglion cell degeneration following ototoxically induced hair cell loss in the guinea pig cochlea

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Published in 2020 at "Hearing Research"

DOI: 10.1016/j.heares.2020.107928

Abstract: Severe damage to the organ of Corti leads to degeneration of the spiral ganglion cells (SGCs) which form the auditory nerve. This degeneration starts at the level of synaptic connection of the peripheral processes (PPs)… read more here.

Keywords: guinea pig; pig cochlea; simultaneous rather; spiral ganglion ... See more keywords
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Induction of experimental autoimmune orchitis by immunization with xenogenic testicular germ cells in mice.

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Published in 2017 at "Journal of reproductive immunology"

DOI: 10.1016/j.jri.2017.04.006

Abstract: We previously showed that immunization of mice with syngeneic or allogeneic testicular germ cells (TGC) alone induces autoimmune inflammation in the testes without using any adjuvant. In the present study, we examined testicular autoimmune response… read more here.

Keywords: guinea pig; autoimmune; murine; tgc ... See more keywords
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Comparative Pharmacokinetics of Three Oximes in a Guinea Pig Model and Efficacy of Combined Oxime Therapy.

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Published in 2020 at "Toxicology letters"

DOI: 10.1016/j.toxlet.2020.01.013

Abstract: Organophosphorus nerve agents (NA) inhibit acetylcholinesterase (AChE) which results in the over-stimulation of both the central and peripheral nervous systems, creating a toxic syndrome that can be lethal if left untreated (Cannard, 2006). It is… read more here.

Keywords: guinea pig; combined oxime; study; efficacy ... See more keywords