LED-phototherapy does not induce oxidative DNA damage in hyperbilirubinemic Gunn rats
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric Research"
DOI: 10.1038/s41390-019-0367-y
Abstract: BackgroundPhototherapy (PT) is the standard treatment of neonatal unconjugated hyperbilirubinemia. Fluorescent tube (FT)-emitted PT light is known to induce oxidative DNA damage in neonates. Nowadays, however, FTs have largely been replaced by light-emitting diodes (LEDs)… read more here.
Keywords: dna damage; induce oxidative; gunn rats; oxidative dna ... See more keywords
Transplanted Human Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Support Liver Regeneration in Gunn Rats.
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DOI: 10.1089/scd.2018.0010
Abstract: Gunn rats bear a mutation within the uridine diphosphate glucuronosyltransferase-1a1 (Ugt1a1) gene resulting in high serum bilirubin levels as seen in Crigler-Najjar syndrome. In this study, the Gunn rat was used as an animal model… read more here.
Keywords: gunn rats; liver; stem; stem cells ... See more keywords