Role of the Gut-Brain Axis in the Shared Genetic Etiology Between Gastrointestinal Tract Diseases and Psychiatric Disorders
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Psychiatry"
DOI: 10.1001/jamapsychiatry.2022.4974
Abstract: Key Points Question To what extent are shared genetic determinants in the comorbidities and associations between gastrointestinal tract diseases and psychiatry disorders involved in the gut-brain axis? Findings In this genome-wide pleiotropic association study using… read more here.
Keywords: brain axis; shared genetic; etiology; gut brain ... See more keywords
Inflammation, Lifestyle Factors, and the Microbiome-Gut-Brain Axis: Relevance to Depression and Antidepressant Action.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical pharmacology and therapeutics"
DOI: 10.1002/cpt.2581
Abstract: Depression is considered a major public health concern, where existing pharmacological treatments are not equally effective across all patients. The pathogenesis of depression involves the interaction of complex biological components such as the immune system… read more here.
Keywords: gut brain; action; brain axis; depression ... See more keywords
Unraveling the Gut‐Brain‐Immune Interplay in Herpes Simplex Virus‐Associated Neurodegeneration
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Medical Virology"
DOI: 10.1002/jmv.70504
Abstract: Herpes simplex virus type 1 (HSV‐1), a ubiquitous neurotropic virus, has been increasingly associated with neurodegenerative disorders through mechanisms extending beyond acute encephalitis to include chronic neuroinflammation, proteostatic disruption, and immune dysregulation. Simultaneously, the gut‐brain‐immune… read more here.
Keywords: brain; hsv; virus; gut brain ... See more keywords
Persistent and newly developed gastrointestinal symptoms after surgery for intestinal malrotation in children: Dysmotility or disorders of gut and brain interaction?
Sign Up to like & getrecommendations! Published in 2024 at "Journal of pediatric gastroenterology and nutrition"
DOI: 10.1002/jpn3.12178
Abstract: OBJECTIVES Surgery for intestinal malrotation (IM) aims to correct the defect and improve symptoms; however, many have persistent gastrointestinal (GI) symptoms postoperatively. We evaluated the incidence, clinical presentation, and long-term outcomes of children with surgically… read more here.
Keywords: diagnosis; disorders gut; intestinal malrotation; gut brain ... See more keywords
The relationship between adverse childhood experiences and disorders of the gut-brain interaction.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of pediatric gastroenterology and nutrition"
DOI: 10.1002/jpn3.12422
Abstract: OBJECTIVES Disorders of the gut-brain interaction (DGBI) arise from a complex interplay of psychosocial factors, altered physiology, and early life factors. In adults, adverse childhood experiences (ACEs) have been associated with DGBI. While both ACEs… read more here.
Keywords: disorders gut; childhood; relationship; brain interaction ... See more keywords
Vulnerability factors for pediatric disorders of gut-brain interaction and implications for functional impairment.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of pediatric gastroenterology and nutrition"
DOI: 10.1002/jpn3.70155
Abstract: OBJECTIVES To evaluate the frequency and number of vulnerability factors for the development of pain-predominant disorders of gut-brain interaction (p-DGBI) in a well-defined cohort of pediatric patients and examine associations with pain severity and functional… read more here.
Keywords: disorders gut; pain; brain interaction; gut brain ... See more keywords
Icariside II Ameliorates Depression Induced by High‐Fat Diet via the Microbiota‐Gut‐Brain Axis in Mice
Sign Up to like & getrecommendations! Published in 2025 at "Phytotherapy Research"
DOI: 10.1002/ptr.70103
Abstract: Obesity can lead to depression via the microbiota‐gut‐brain axis. Icariside II (ICS II), a flavonoid compound derived from the traditional Chinese medicine Herbal Epimedium, exerts excellent neuroprotective effects. However, the pharmacological effects and underlying mechanisms… read more here.
Keywords: brain; microbiota gut; depression; gut brain ... See more keywords
The gut–brain axis in early Parkinson’s disease: from prodrome to prevention
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Neurology"
DOI: 10.1007/s00415-025-13138-5
Abstract: Parkinson’s disease is the second most common neurodegenerative disorder and fastest growing neurological condition worldwide, yet its etiology and progression remain poorly understood. This disorder is characterized pathologically by the prion-like spread of misfolded neuronal… read more here.
Keywords: parkinson; parkinson disease; gut brain;
[From gut feeling to visceral pain : Effects of negative expectations in the context of the gut-brain axis].
Sign Up to like & getrecommendations! Published in 2021 at "Schmerz"
DOI: 10.1007/s00482-021-00614-w
Abstract: Disturbances of the gut-brain axis are characterized by complex dysfunctions on peripheral and central nervous system levels, which can contribute to visceral hypervigilance and hyperalgesia and imprint visceral pain. Numerous cognitive, emotional and psychoneurobiological factors… read more here.
Keywords: gut brain; visceral pain; brain axis; pain ... See more keywords
The Role of Epigenomic Regulatory Pathways in the Gut-Brain Axis and Visceral Hyperalgesia.
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and molecular neurobiology"
DOI: 10.1007/s10571-021-01108-0
Abstract: The gut-brain axis (GBA) is broadly accepted to describe the bidirectional circuit that links the gastrointestinal tract with the central nervous system (CNS). Interest in the GBA has grown dramatically over past two decades along… read more here.
Keywords: visceral hyperalgesia; hyperalgesia; brain axis; epigenomic regulatory ... See more keywords
Sex Differences in the Gut-Brain Axis: Implications for Mental Health
Sign Up to like & getrecommendations! Published in 2020 at "Current Psychiatry Reports"
DOI: 10.1007/s11920-020-01202-y
Abstract: Purpose of Review The purpose of this article is to highlight how sex differences in the gut-brain axis may contribute to the discrepancies in incidence of neurodevelopmental, psychiatric, and neurodegenerative disorders between females and males.… read more here.
Keywords: differences gut; sex differences; brain axis; sex ... See more keywords