2′-Fucosyllactose impacts the expression of mucus-related genes in goblet cells and maintains barrier function of gut epithelial cells
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2021.104630
Abstract: Abstract Scope Cost-effective microbial biosynthesis of 2′-fucosyllactose (2′-FL) allows its application in infant formula. The specific effects of 2′-FL on the gastrointestinal immune barrier are still largely unknown. Methods/results Here, we quantified and compared the… read more here.
Keywords: mucus related; expression mucus; related genes; goblet cells ... See more keywords
EGFR-dependent TOR-independent endocycles support Drosophila gut epithelial regeneration
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms15125
Abstract: Following gut epithelial damage, epidermal growth factor receptor/mitogen-activated protein kinase (EGFR/MAPK) signalling triggers Drosophila intestinal stem cells to produce enteroblasts (EBs) and enterocytes (ECs) that regenerate the gut. As EBs differentiate into ECs, they become… read more here.
Keywords: egfr dependent; regeneration; dependent tor; growth ... See more keywords
Gut epithelial cell-derived exosomes trigger posttrauma immune dysfunction
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DOI: 10.1097/ta.0000000000001748
Abstract: BACKGROUND Exosomes are extracellular vesicles that act as endogenous mediators of the immune response. We have previously shown that exosomes released into mesenteric lymph (ML) following trauma (T)/hemorrhagic shock (HS) induce proinflammatory cytokine production in… read more here.
Keywords: epithelial cell; dysfunction; posttrauma immune; immune dysfunction ... See more keywords
Polyamines in Gut Epithelial Renewal and Barrier Function.
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DOI: 10.1152/physiol.00011.2020
Abstract: Polyamines regulate a variety of physiological functions and are involved in pathogenesis of diverse human diseases. The epithelium of the mammalian gut mucosa is a rapidly self-renewing tissue in the body, and its homeostasis is… read more here.
Keywords: barrier; renewal barrier; barrier function; epithelial renewal ... See more keywords
Novel Iron-Whey Protein Microspheres Protect Gut Epithelial Cells from Iron-Related Oxidative Stress and Damage and Improve Iron Absorption in Fasting Adults
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DOI: 10.1159/000480632
Abstract: Background: Iron food fortification and oral iron formulations are frequently limited by poor absorption, resulting in the widespread use of high-dose oral iron, which is poorly tolerated. Methods: We evaluated novel iron-denatured whey protein (Iron-WP)… read more here.
Keywords: absorption; whey protein; iron; novel iron ... See more keywords